摘要
目的探讨我院综合措施干预对围手术期预防用抗菌药物使用的有效性,了解围手术期抗菌药物管理和干预措施的效果。方法选取我院2014年7月~2015年6月收治的125例I类手术患者为干预前组,并选取2015年7月~2016年6月收治的130例I类手术患者为干预后组,其中干预组Ⅰ类切口手术围手术期预防用抗菌药物干预,分析干预效果。结果Ⅰ类切口围手术期抗菌药物预防使用率由48.8%降到28.5%、药物选择不当率由78.7%降至43.2%,给药时机不当由29.5%降至10.8%,用药疗程不合理率由44.3%降至27.0%、剂量与用法不合理由24.6%降至5.4%;呈不断下降趋势,差异均有统计学意义(P<0.05)。结论干预措施对减少抗菌药物应用的不合理因素有了明显改善,但仍存在药物选择不合理,无指征用药、用药疗程过长等现象,需进一步加强干预和监管。
Objective To investigate the effectiveness of the use of antibacterial drugs in perioperative prevention and intervention of clinical pharmacists, to investigate the effects of perioperative administration of antibiotics and intervention measures. Methods From July 2014 to January 2015were 125 patients with type Ⅰ surgery for the intervention group, and select the records of 130 cases of the same type Ⅰ surgery patients in intervention group, the intervention group Ⅰ class incision surgery perioperative preventive intervention with antibacterial drugs, analysis of intervention effect. Results Type Ⅰ incision perioperative antibiotic prophylaxis was reduced from 48.8% to 33.1%, improper drug selection rate from 83.8% to 30：4%, improper time of administration from 43.7% to32.6%. The course of treatment is not reasonable rate from57.2% tol3.0%,the dosage and usage of different reasons of 10.8% to6.5%, unreasonable combined use 2.7% to 0; there was a decreasing trend, statistically significant difference Significance （P 〈 0.05）. Conclusion Intervention measures to reduce antimicrobial drug use irrational factors have significantly improved, but there are still irrational drug choice, no indication of medicine, course of treatment was too long and so on, to further strengthen the regulatory intervention and.
出处
《中国医药科学》
2017年第1期91-93,共3页
China Medicine And Pharmacy
关键词
Ⅰ类切口手术
抗菌药物
干预
合理用药
Type Ⅰ incision surgery
Antimicrobial agents
Intervention
Rational use of drugs
