摘要
目的:研究糜烂型口腔扁平苔藓应用他克莫司治疗的效果、不良反应发生率和复发率等。方法:将2015年1月-2016年4月笔者所在医院确诊的70例糜烂型口腔扁平苔藓患者随机纳入观察组(他克莫司软膏)和对照组(丙酸氯倍他素软膏)中,每组35例,观察记录所有患者的临床疗效、不良反应发生率和复发率等。结果:观察组患者的治疗总有效率、不良反应发生率、复发率比较,差异无统计学意义(P>0.05)。结论:他克莫司和丙酸氯倍他素在糜烂型口腔扁平苔藓的治疗中具有高效安全的特点,可在治疗中交替使用,其临床应用价值较高。
Objective：To explore the clinical efficacy,incidence of adverse reactions and recurrence rate about the treatment of oral lichen planus of erosive type with Tacrolimus.Method：Seventy patients with oral lichen planus of erosive type were regard as research group from January 2015 to April 2016 in our hospital which were divided into observation group（Tacrolimus Ointment） and control group（Clobetasol Propionate Cream） equally.The clinical efficacy,incidence of adverse reactions and recurrence rate of all the patients were observed and recorded.Result：The differences in the clinical efficacy,incidence of adverse reactions and recurrence rate between the two groups were not statistically significant（P〉0.05）.Conclusion：In the treatment of oral lichen planus of erosive type,Tacrolimus Ointment and Clobetasol Propionate Cream are both safe and effective with an ideal substitutability in the treatment,so their clinical application value are considerable.
作者
林丽凡
LIN Li-fan(Guangdong Hydropower Hospital, Guangzhou 511340, China)
出处
《中外医学研究》
2017年第6期10-12,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
他克莫司
丙酸氯倍他素
糜烂型口腔扁平苔藓
临床效果
Tacrolimus
Clobetasol Propionate
Oral lichen planus of erosive type
Clinical efficacy
