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维持性血液透析病人抑郁与血白蛋白及血肌酐等指标的相关性研究 被引量:6

Study on correlation between depression and serum albumin and creatinine of patients with maintenance hemodialysis
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摘要 [目的]探讨维持性血液透析病人(MHD)抑郁状况与血白蛋白及血肌酐等指标的关系。[方法]应用Zung抑郁自评量表将73例MHD病人分为抑郁组和非抑郁组,比较两组病人血白蛋白(Alb)、血肌酐(Scr)等生化指标的差异,并分析其与抑郁评分的相关关系,应用二项Logistic回归方程分析抑郁发生的独立危险因素。[结果]抑郁41例,非抑郁32例,抑郁发生率为56.2%;抑郁组和非抑郁组之间的Alb、Scr差异有统计学意义(P<0.05);抑郁评分与Alb、Scr呈负相关;Logistic回归方程分析显示Alb和Scr为抑郁发生的独立危险因素。[结论]MHD病人抑郁发生率高且与Alb、Scr密切相关,Alb和Scr为抑郁发生的独立危险因素。 Objective:To probe into the relationship between depression and serum albumin and creatinine of patients with maintenance hemodialysis(MHD).Methods:A total of 73 MHD patients were divided into depression group and non depression group with Zung self-assessment depression scale;serum albumin(Alb),serum creatinine(Scr)and other biochemical indexes were compared between the two groups,and the correlation between the biochemical indexes and the depression score was analyzed.The independent risk factors of depression with MHD were analyzed by using Bilogistic regression equations.Results:41cases of patients with depression,32 cases without depression,the incidence of depression was 56.2%.The difference of albumin(Alb)and serum creatinine(Scr)was statistically significant between the two groups(P〈0.05).A significant negative correlation between depression score and serum Alb and Scr was showed.Logistic regression analysis showed that Alb and Scr were independent risk factors for depression in patients with MHD.Conclusion:The incidence of depression in MHD patients was higher than general population,and it was closely related with Alb and Scr,and Alb and Scr were independent risk factors for depression in patients with MHD.
出处 《全科护理》 2017年第5期516-519,共4页 Chinese General Practice Nursing
基金 2015年深圳市南山区科技计划项目 编号:2015039
关键词 维持性血液透析 抑郁 血白蛋白 血肌酐 maintenance hemodialysis depression serum albumin serum creatinine
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