摘要
目的探讨小儿豉翘颗粒联合利巴韦林气雾剂治疗手足口病的临床治疗效果。方法选择2015年2月至2016年2月湖南省儿童医院感染科收治的手足口病患儿78例,随机分为观察组和对照组各39例。对照组采用利巴韦林气雾剂治疗,观察组在对照组治疗基础上联合小儿豉翘颗粒治疗。治疗7d后,观察两组治疗效果、症状体征消失时间及不良反应情况。结果观察组总有效率为97.44%(38/39),显著高于对照组74.36%(29/39),差异有统计学意义(P<0.05)。观察组患儿退热时间、皮疹消退时间和痊愈时间均短于对照组,差异有统计学意义(P<0.05)。观察组患儿不良反应发生率为2.56%(1/39),显著低于对照组23.08%(9/39),差异有统计学意义(P<0.05)。结论采用小儿豉翘颗粒联合利巴韦林气雾剂临床治疗小儿手足口病,具有较高的疗效,并且临床不良反应发生率较低,安全性很高,用药较为方便简单,因而可将其广泛地推广至临床治疗中。
Objective To explore the clinical effect of soybean granule combined with ribavirin aerosol for children with hand-foot-mouth disease（HFMD）.Methods A total of 78 children with HFMD,who were treated in our hospital from February 2015 to February 2016,were randomly divided into observation group and control group（39cases in each group）.The patients in the control group were treated with aerosolized ribavirin.The patients in the observation group were treated with the combination of children＇s soybean granules and ribavirin aerosol.Seven days after treatment,the effect in the two groups of pediatric patients,the corresponding clinical signs and symptoms and the adverse reactions were compared.Results The total effective rate was 97.44% in the observation group and 82.05% in the control group.The total effective rate in the observation group was significantly higher than that in the control group（P〈0.05）.The time of fever subsidence,the time of rash disappearance and the recovery time were shorter in the observation group than in the control group.There was significant difference between the two groups（P〈0.05）.The adverse reaction rate was 2.56%in the observation group and 23.08%in the control group.There was a significant difference between the two groups（P〈0.05）.Conclusion The treatment for pediatric hand-foot-mouth disease with the combination of pediatric soybean granules and ribavirin aerosol have a high efficacy and a low incidence of clinical adverse reactions,with high safety and convenient and simple administration.It should be promoted in clinical treatment.
作者
于四景
YU Sijing.(Department of Infectious Diseases, Childrer＇s Hospital of Hunan Province, Chang- sha 410007, China)
出处
《中国中西医结合儿科学》
2017年第1期67-69,共3页
Chinese Pediatrics of Integrated Traditional and Western Medicine
关键词
手足口病
小儿豉翘颗粒
利巴韦林气雾剂
疗效分析
儿童
Hand-foot-mouth disease
Pediatric soybeans granule
Ribavirin aerosol
Curative effect analysis
Children
