摘要
作为普遍存在于真核生物细胞内的一种机制,细胞自噬能对内环境稳定进行自我维持,且在生长、发育、细胞自我保护等多种生理活动中发挥着重要的作用。而炎症反应的发生在很大程度上与细胞自噬有着密切关系。文章主要对自噬与炎症的相关作用进行综述,并对自噬与炎症在眼科疾病中的研究进行了分析,为临床上相关疾病的研究提供新的思路。
As a mechanism that widely exists in eukaryotic cells,autophagy sustains a stable internal cellular environment and plays an important role in many physiological activities such as growth,development and self-protection. The inflammatory reaction has close relationship with cell autophagy. This paper reviewed the association of autophagy with inflammation,and analyzed the researches on autophagy and inflammation in eye disorders,to provide a renewed view for further clinical researches on related diseases.
作者
杜军辉
李蓉
马楼艳
侯鹏飞
Du Junhui Li Rong Ma Louyan Hou Pengfei(Department of Ophthalmology, Xi＇an Ninth Hospital, Xi＇an, Shaanxi 710054 Department of Ophthalmology, The Affiliated Hospital of Xi＇an Medical University, Xi＇an , Shaanxi 710077, Chin)
出处
《临床眼科杂志》
2017年第1期91-94,共4页
Journal of Clinical Ophthalmology
基金
西安市社会发展引导计划-医学研究项目(No.SF1508(3))
陕西省自然科学基础研究计划-面上项目(No.2016JM8018)
国家自然科学基金青年项目(No.81500726)
关键词
细胞自噬
炎症
炎性小体
TOLL样受体
Cell autophagy
Inflammation
Inflammasome
Toll-like receptors
