摘要
目的探讨腹腔镜与开腹行子宫广泛性切除术治疗Ⅰa2~Ⅱb期子宫颈癌的临床效果。方法选取2010年12月至2015年12月间四川省达州市渠县人民医院收治的92例Ⅰa2~Ⅱb期子宫颈癌患者,采用随机数字表法分为观察组与对照组,每组46例。观察组患者行腹腔镜子宫广泛性切除术,对照组患者行开腹子宫广泛性切除术,比较两组患者手术效果及术后并发症。结果观察组患者手术时间为(153.8±31.6)min,术中出血量为(208.3±41.2)ml,术中输液量为(1342.7±179.2)ml,术后排气时间为(1.6±0.4)d,术后发热时间为(2.0±0.8)d,下床活动时间为(1.8±0.5)d,留置尿管时间为(13.7±2.0)d,术后住院时间为(16.2±2.3)d,均少于对照组的(198.7±25.4)min、(356.1±60.7)ml、(1859.4±214.3)ml、(2.8±0.7)d、(2.7±0.9)d、(2.6±0.7)d、(16.6±1.8)d和(20.4±2.6)d,两组比较,差异均有统计学意义(均P<0.05)。观察组患者术中尿量为(337.5±69.4)ml,清除淋巴结数量为(13.2±2.6)枚,均多于对照组的(251.8±71.0)ml和(11.0±1.8)枚,观察组患者术后并发症发生率为2.2%,低于对照组的15.2%,两组比较,差异均有统计学意义(均P<0.05)。结论腹腔镜比开腹行子宫广泛性切除术疗效更佳,安全性更高。
Objective To investigate clinical efficacy of laparoscopic versus open extensive hysterectomy for stage Ⅰa2 ~ Ⅱb cervical cancer. Methods Ninety-two patients with stage Ⅰa2 ~ Ⅱb cervical cancer were selected at People's Hospital of Qu County from December 2010 to December 2015. These patients were divided into an observation group and a control group with 46 patients in each group. Patients in the observation group underwent laparoscopic extensive hysterectomy and patients in the control group underwent open extensive hysterectomy. Surgical efficacy indications and postoperative complications were compared between the two groups. Results Operation time was( 153. 8 + 31. 6) min,intraoperative blood loss( 208. 3 + 41. 2) ml,intraoperative infusion quantity( 1342. 7 + 179. 2) ml,postoperative exhaust time( 1. 6 ± 0. 4) d,postoperative fever time( 2. 0 + 0. 8) d,ambulation time( 1. 8 + 0. 5) d,time placing a urinary catheter( 13. 7 + 2. 0) d and postoperative length of hospital stay( 16. 2 + 2. 3) d for the observation group,which were less than( 198. 7 + 25. 4) min,( 356. 1 + 60. 7) ml,( 1859. 4 + 214. 3) ml,( 2. 8 +0. 7) d,( 2. 7 + 0. 9) d,( 2. 6 + 0. 7) d,( 16. 6 + 1. 8) d and( 20. 4 + 2. 6) d of the control group respectively( all P 0. 05). Intraoperative urinary volume was( 337. 5 + 69. 4) ml and number of lymph nodes removed was( 13. 2 + 2. 6) for the observation group,which was higher than( 251. 8 + 71. 0) ml and( 11. 0 +1. 8) of the control group respectively. Postoperative complication rate was 2. 2% which was lower than15. 2% of the control group( all P 0. 05). Conclusion Laparoscopic hysterectomy is superior to open hysterectomy for stage Ⅰa2 ~ Ⅱb cervical cancer with higher security.
作者
王德蓉
赵学学
覃群英
WANG De-rong ZHAO Xue-xue QIN Qun-ying(Department of Obstetrics and Gynecology, People's Hospital of Qu County,Dazhoa 635200,Chin)
出处
《中国肿瘤临床与康复》
2017年第2期188-190,共3页
Chinese Journal of Clinical Oncology and Rehabilitation