摘要
目的观察四磨汤联合西药治疗功能性消化不良(FD)肝气犯胃证的临床疗效。方法将90例FD肝气犯胃证患者随机分为对照组、西药治疗组、联合治疗组3组,各30例。对照组给予莫沙必利,5 mg/次,3次/d;西药治疗组在对照组治疗方法的基础上给予枸橼酸坦度螺酮,10 mg/次,3次/d;联合治疗组在西药治疗组治疗方法的基础上联合四磨汤口服液,20 mL/次,3次/d。3组均于治疗4周及8周后判定疗效。结果治疗4周及8周后,西药治疗组及联合治疗组的总有效率均显著高于对照组,差异均有统计意义(P<0.05);治疗8周后,联合治疗组显效率显著高于西药治疗组,2组比较差异有统计意义(P<0.05)。3组均未发生严重不良反应。结论四磨汤联合西药治疗FD肝气犯胃证临床疗效显著,疗效优于西药枸橼酸坦度螺酮和/或莫沙必利,且无明显不良反应,值得临床推广应用。
Objective To observe the effect of Simo Tang combining western medicine on stomach disorder due to liver qi of functional dyspepsia（ FD）. Methods 90 patients with stomach disorder due to liver qi of FD were randomly divided into 3 groups,30 cases in each. The control group was given mosapride,5 mg each time,3times a day; western medicine treatment group took tandospirone citrate,10 mg each time,3 times a day; based on that,the combined treatment group was intervened with Simotang Oral Liquid,20 m L each time,3 times a day. Clinical efficacys of 3 groups were observed after 4 and 8 weeks of treatment. Results On 4thand 8thweek after treatment,the total effective rates of western medicine treatment group and combined treatment group were notably higher than that of control group,the difference was significant（ P〈0.05）. On 8thweek,the significant efficiency of combined treatment group was higher than that of western medicine treatment group,there was a statistical significance（ P〈0.05）. All patients had no any serious adverse reactions. Conclusion The combined therapy has a good efficiency without any adverse reactions. It is worthy of clinical application.
作者
范伏岗
浦俭斌
丁一村
曹勤
FAN Fugang PU Jianbin DING Yicun CAO Qin(Digestive System Department, Putuo Hospital of Shanghai University of Chinese Medicine, Shanghai, 200062, Chin)
出处
《甘肃中医学院学报》
2017年第1期38-41,共4页
Journal of Gansu College of Traditional Chinese Medicine
关键词
功能性消化不良
肝气犯胃证
四磨汤
枸橼酸坦度螺酮
莫沙必利
临床观察
functional dyspepsia
stomach disorder due to liver qi
Simo Tang
tandospirone citrate
mosapride
clinical observation
