摘要
[目的]评价海宁市结直肠癌早诊早治筛查效果。[方法]根据《癌症早诊早治项目技术方案》,对40~74岁目标人群采用危险因素量化评估问卷调查和两次大便隐血试验(FOBT)进行初筛,在此基础上,确定结直肠癌高危人群,然后,用电子结肠镜作进一步精筛,对查出的肠道病变进行及时干预。[结果]2007~2012年海宁市结直肠癌筛查目标人群为322 034人,完成病史问卷调查286 470例,顺应率为88.96%;其中病史阳性16 807例,阳性率为5.87%;两次大便隐血试验461 348份,其中阳性25 928份,阳性率为5.62%。经初筛确定高危人群40 103人需进一步作结肠镜精筛。完成结肠镜检查29 069例,顺应率为72.90%;共检出肠道病变(息肉、腺瘤、癌)7408例,检出率25.48%,其中进展期以上病变1570例。病史阳性占检出病例数的41.10%,FOBT阳性占58.90%,而在205例结直肠癌中FOBT阳性占了91.71%。[结论 ]结直肠癌筛查成效显著,使无症状的结直肠癌及癌前期病变患者能够实现"三早",减轻家庭和社会疾病负担。
[Purpose] To investigate the results of early diagnosis and early treatment of colorectal cancer in Haining city. [Methods] According to Cancer Early Diagnosis and Early Treatment Project,40 ~74 years old target population with a history of risk factors for quantitative assessment questionnaire and two times of fecal occult blood test（FOBT） were screened. On this basis,the high-risk person with colorectal cancer underwent with electronic colonoscopy for further fine sieve to detect intestinal diseases and timely intervention. [Results] From 2007 to 2012,the target population for colorectal cancer screening were 322 034,including completing medical history questionnaire in 286 470 cases;the compliance rate was 88.96%. The history was positive in 16 807 cases,the positive rate was 5.87%;two times of fecal occult blood test in 461 348 cases,among them,25 928 cases were positive with the positive rate of 5.62%. By screening the high risk population identified 40 103 patients needed further colonoscopy screening. Colonoscopy underwent in29 069 cases,the compliance rate was 72.90%,there were intestinal lesions（polyps,adenoma,carcinoma） in 7408 cases,the detection rate was 25.48%,including 1570 cases with more advanced lesions. The positive history of detected cases accounted for 41.10%,FOBT positive accounted for58.90%. While in 205 cases of colorectal cancer,FOBT positive accounted for 91.71%. [ Conclusion] Colorectal cancer screening has significant effect,so that asymptomatic patients with colorectal cancer and precancerous lesions can achieve early diagnosis and early treatment,to reduce the family and social disease burden.
出处
《中国肿瘤》
CAS
CSCD
2017年第3期181-184,共4页
China Cancer
基金
公共卫生中央财政转移支付项目(卫疾控非传便函[2005]151号)
关键词
结直肠肿瘤
早诊早治
人群筛查
colorectal neoplasms
early diagnosis and early treatment
population screening
