摘要
目的探讨Revolution CT轴位扫描全肝灌注"一站式"成像的可行性。方法选取19例患者行Revolution CT上腹部增强检查,获得全肝CT灌注(CTP)图像、静脉期及平衡期图像。于CTP图像上由2名观察者分别确定腹主动脉与门静脉主干时间-密度曲线(TDC)峰值对应的rank值及CT值,定量测量肝左、右叶灌注参数血流量(BF)、血容量(BV)、平均通过时间(MTT)、达峰时间(TP)、肝动脉分数(HAF)。采用腹主动脉和门静脉TDC峰值所对应的图像重组肝动脉CTA、门静脉CTV,并提取动脉期图像。记录CT灌注和"一站式"检查的辐射剂量。比较肝左、右叶灌注参数的差异,并对2名观察者的结果进行一致性分析。结果肝左叶、右叶的BF和MTT值差异有统计学意义(P均<0.05);2名观察者对肝动脉CTA、门静脉CTV及动脉期图像的主观评分均≥2分,一致性良好(Kappa值均>0.6)。灌注期和"一站式"检查有效辐射剂量分别为14.47mSv、21.29mSv。结论 Revolution CT轴位全肝灌注"一站式"成像,在保证较低辐射剂量的前提下,可获得肝脏CTP的多个定量参数,又可提供清晰的肝动脉CTA、门静脉CTV和3期增强扫描图像,具有广阔的临床应用前景。
Objective To explore the feasibility of axial whole-liver one-stop examination with Revolution CT.Methods Totally 19 patients were underwent upper-abdominal enhanced examination with Revolution CT and acquired whole-liver CT perfusion（CTP）,vein phase and balanced phase enhanced images.Two observers recorded the rank and peak CT value corresponding to time-density curve（TDC）of abdominal aorta and portal vein respectively on the CTP images.The perfusion parameters including blood flow（BF）,blood volume（BV）,hepatic arterial fraction（HAF）,mean transit time（MTT）,time to peak（TP）of left and right liver lobe were measured.The images of hepatic artery CTA and portal vein CTV were reconstructed and the arterial phase enhanced images were extracted using the images corresponding to abdominal aorta and portal vein peak TDC.And the radiation dose of CT perfusion and one-stop examination were recorded.The differences between perfusion parameters of left and right liver lobe were compared and the consistency of two observers were analyzed.Results The differences between BV and MTT of left and right liver lobe were statistical significance（both P〈0.05）.The subjective scores of hepatic artery CTA,portal vein CTV and arterial phase images were greater than 1point.The two observers were in great consistence（Kappa〉0.6）.The effective radiation dose in perfusion phase and one-stop examination were 14.47 mSv and 21.29 mSv.Conclusion With low radiation dose,Revolution CT axial wholeliver perfusion one-stop examination can provide multiple quantitative parameters of liver CTP and clear hepatic artery CTA,portal vein CTV and 3 phase enhanced scan images,which has broadly prospective in clinical application.
出处
《中国医学影像技术》
CSCD
北大核心
2017年第3期462-467,共6页
Chinese Journal of Medical Imaging Technology
