摘要
目的:研究甲胎蛋白异质体检测在肝癌及肝病患者中诊断价值。方法:选取2014年2月至2014年10月期间接诊的40例肝癌患者以及40例肝病患者作为研究对象,其中40例肝癌患者作为观察组,40例肝病患者作为对照组,检测两组患者的甲胎蛋白(ɑ-fetoprotein,AFP)、甲胎蛋白L3(ɑ-fetoprotein-L3,AFP-L3)/AFP、AFP-L3阳性率、AFP阳性率等指标值,并对其结果进行比较分析。结果:观察组患者的AFP、AFP-L3/AFP等指标值均高于对照组患者(P<0.05),观察组患者的AFP-L3阳性率、AFP阳性率高于对照组患者(P<0.05)。结论:甲胎蛋白异质体检测在肝癌及肝病的诊断中具有重要的临床意义,可以有效区分肝癌和慢性肝病,为肝癌诊断提供了重要的参考依据,有效提高了肝癌的检出率,弥补了肝癌检测的不足,具有重要的临床应用价值。
Objective：To study the diagnostic value of alpha fetoprotein heteroplasm detection in patients with liver cancer and liver disease. Methods： 40 cases of hepatoeellular carcinoma and 40 cases of liver disease admitted from February 2014 to October 2014 were enrolled in this study, the former as the study group, and the latter as the contl^l group. AFP, AFP - L3 / AFP, and the positive rate of AFP - L3 and AFP in the two groups were determined and comparatively analyzed. Results ： The AFP and AFP - L3 / AFP in the study group were significantly higher than those in the control group （ P 〈0.05 ）. The positive rate of AFP- L3 and AFP in the study group was significantly higher than that of the control group （ P 〈 0.05 ）. Conclusion ： The detection of alpha - fetoprotein heteroplasm in the diagnosis of hepatocellular carcinoma and liver disease has important clinical significance, which can effectively improve the detection rate of patients with liver cancer, and make up for the deficiency of the liver cancer detection, with important clinical application value.
出处
《包头医学院学报》
CAS
2017年第3期54-55,共2页
Journal of Baotou Medical College
关键词
甲胎蛋白异质体检测
肝癌
肝病
诊断价值
AFP heteroplasm detection
Liver cancer
Liver disease
Diagnostic value
