摘要
目的了解新生儿双胎体重不均衡发生情况并探讨其妊娠相关危险因素,为新生儿双胎体重不均衡的预防提供依据。方法收集2010年1月至2015年1月在我院分娩并存活的双胎,以新生儿双胎出生体重相差20%为界分为体重不均衡组（≥20%）和体重均衡组（〈20%）,查询病历并收集双胎及其母亲妊娠期间相关信息,采用单因素和多因素非条件Logistic回归模型,回顾性分析双胎体重不均衡的危险因素。结果共纳入648对（1 296例）双胎新生儿,其中体重不均衡组65对,占10%。体重不均衡组新生儿（130例）平均出生体重、身长、1 min Apgar评分均低于体重均衡组,母亲年龄高于体重均衡组,差异有统计学意义（P〈0.05）;脐带异常（OR=2.115,95%CI 1.177-3.800）、母亲妊娠期贫血（OR=2.326,95%CI 1.079-5.016）、羊水量异常（OR=3.152,95%CI 1.063-9.348）、双胎性别不同（OR=2.073,95%CI 1.200-3.581）和高龄产妇（OR=2.467,95%CI 1.285-4.733）可能是双胎体重不均衡的危险因素。结论双胎体重不均衡的发生率为10%,脐带异常、母亲妊娠期贫血、羊水量异常、双胎性别不同和高龄产妇可能是双胎体重不均衡的危险因素。
Objective To study the incidence and pregnancy associated risk factors of twins with discordant birthweight,and to provide guidelines for the prevention of discordant birthweight between twins. Methods Retrospective analysis was conducted on newborn twins born in our Hospital between January 2010 and January 2015. Twins with birth weight difference ≥20% were designated as discordant group,and twins with birth weight difference 20%,concordant group. The relevant information of newborn twins and the mother during pregnancy were collected. Logistic regression was used to analyze the risk factors of birthweight discordance. Results A total of 648 pairs of twins were studied. 65 pairs（ 10. 0%） of discordant twins were collected. Birth weight,body length and Apgar score of discordant group were lower than that of the concordant group（ P〈0. 05）. The maternal age of discordant group was higher than that of the concordant group（ P〈0. 05）. Multivariate logistic regression analysis indicated that following factors have higher risk of discordant birthweight of twins： abnormality of umbilical cord（ OR = 2. 115,95% CI 1. 177- 3. 800）,anemia（ OR = 2. 326,95% CI 1. 079-5. 016）,abnormal volume of amniotic fluid（ OR = 3. 152,95% CI 1. 063- 9. 348）,twins with different genders（ OR = 2. 073,95% CI 1. 200- 3. 581）,and advanced maternal age（ OR = 2. 467,95% CI1. 285- 4. 733） during pregnancy. Conclusions The incidence of discordant birthweight in twins was10. 0%. Abnormality of umbilical cord,anemia,abnormal volume of amniotic fluid,twins with different genders,and advanced maternal age during pregnancy were possible risk factors.
出处
《中国新生儿科杂志》
CAS
2016年第6期438-441,共4页
Chinese Journal of Neonatology
关键词
妊娠
双胎
出生体重
危险因素
婴儿
新生
Pregnancy
twin
Birth weight
Risk factors
Infant
newborn
