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雷公藤多甙片与地氯雷他定联合治疗慢性特发性荨麻疹的效果研究 被引量:7

Study on the Effect of Tripterygium Wilfordii Combined with Desloratadine in Treatment of Chronic Idiopathic Urticaria
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摘要 目的:分析研究雷公藤多甙片与地氯雷他定联合治疗慢性特发性荨麻疹的临床效果。方法:选取2014年3月-2015年2月笔者所在医院收治的慢性特发性荨麻疹患者90例作为本次研究对象,随机将患者分为对照组和观察组,每组45例。对照组患者单纯给予地氯雷他定治疗,观察组给予雷公藤多甙片与地氯雷他定联合治疗,比较两组患者的临床治疗效果。结果:(1)对照组患者治疗有效31例(68.89%),观察组患者治疗有效40例(88.89%),观察组患者的临床治疗效果明显好于对照组,差异有统计学意义(字2=5.404,P<0.05)。(2)对照组患者治疗后发生不良反应4例(8.89%);观察组患者治疗后发生不良反应2例(4.44%),两组患者治疗后发生不良反应例数比较差异无统计学意义(字2=0.714,P>0.05)。结论:雷公藤多甙片与地氯雷他定联合治疗慢性特发性荨麻疹,临床治疗总有效率要显著高于单纯使用地氯雷他定患者,且无显著不良反应,安全可靠,具有很好的临床效果。 Objective:To analyze the clinical effect of Tripterygium Wilfordii combined with Desloratadine in treatment of chronic idiopathic urticaria.Method:From January 2015 to April 2016 in the author's hospital,90 cases of patients with chronic idiopathic urticaria were sellected as the research object,the patients were randomly divided into control group and observation group,with 45 patients in each group.Patients in the control group were only given Desloratadine treatment,and patients in the observation group were given Tripterygium Wilfordii combined with Desloratadine treatment,the clinical curative effect of two groups were compared.Result:In the control group,31 cases(68.89%) were effective,and 40 cases(88.89%) were effective in the observation group.The clinical treatment effect of the observation group was significantly better than that of the control group,the difference was statistically significant( 字2=5.404,P0.05).Adverse reactions occurred in 4 cases(8.89%) in control group after treatment,adverse reactions occurred in 2 cases(4.44%) after treatment.There was no significant difference in the number of adverse reactions after treatment between two groups( 字2=0.714,P〉0.05).Conclusion:GTW tablet combined with Desloratadine in treatment of chronic idiopathic urticaria,the clinical treatment efficiency will appear more than that of Desloratadine in patients,has no significant adverse reaction,safe and reliable, has good clinical effect.
作者 陈涛
机构地区 盐亭县人民医院
出处 《中外医学研究》 2017年第7期24-26,共3页 CHINESE AND FOREIGN MEDICAL RESEARCH
关键词 雷公藤多甙片 地氯雷他定 慢性特发性荨麻疹 Tripterygium Wifordii Desloratadine Chronic idiopathic urticaria
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