摘要
目的探讨布比卡因联合小剂量舒芬太尼腰-硬麻醉镇痛对瘢痕妊娠剖宫产产妇血清β-人绒毛膜促性腺激素(β-HCG)水平及大出血的影响。方法选择2014年1月-2015年6月我院收治的瘢痕妊娠剖宫产者112例,按麻醉方法分为研究组和对照组,每组56例。研究组给予布比卡因联合小剂量舒芬太尼腰-硬麻醉镇痛,对照组给予布比卡因联合与舒芬太尼同等剂量的葡萄糖腰-硬麻醉镇痛。观察2组麻醉开始、分娩结束血清β-HCG水平及大出血发生情况。结果麻醉开始2组血清β-HCG水平比较差异无统计学意义(P>0.05);分娩结束研究组血清β-HCG水平低于对照组,差异有统计学意义(P<0.01)。研究组不良情况及产后出血发生率低于对照组,差异有统计学意义(P<0.05)。结论布比卡因联合小剂量舒芬太尼腰-硬麻醉镇痛能有效降低瘢痕妊娠剖宫产产妇血清β-HCG水平,减少分娩后不良情况及大出血的发生。
Objective To explore the effect of bupivacaine combined with low-dose sufentanil on the serum β-HCG level and bleeding rate during cesarean section of scarred uterine. Methods A total of 112 cases of cesarean section scar pregnancy treated in our hospital between January 2014 and June 2015 were selected and divided into study group （ n = 56 ） and control group （n = 56）. The study group was given small-dose bupivacaine combined with small-dose sufentanil for spinal -epidural an- esthesia while the control group was given bupivacaine combined with glucose at the same dose of sufentanil for spinal-epidural anesthesia. Serum β-HCG levels and bleeding rate after anesthesia and delivery in the two groups were observed. Results There was no significant difference in the serum β-HCG level in the two groups before anesthesia（ P〉0.05 ）, but after delivery, it was lower in study group than that in control group （ P〈0.01 ）. The incidence of adverse events and bleeding rate in study group were lower than those in control group （ P〈0.05 ）. Conclusion Bupivacaine combined with low - dose sufentanil can effectively reduce not only the serum β- HCG level during cesarean section of scarred uterine, but also the occurrence of postoperative adverse conditions and bleeding.
出处
《解放军预防医学杂志》
CAS
2017年第2期178-180,共3页
Journal of Preventive Medicine of Chinese People's Liberation Army
关键词
布比卡因
舒芬太尼
腰-硬麻醉镇痛
剖宫产术
再
Β人绒毛膜促性腺激素
bupivacaine
sufentanii
combined spinal and epidural analgesia
cesarean section, repeat
β-human chorionic gonadotropin
