摘要
目的探讨氨溴特罗口服溶液联合孟鲁司特钠咀嚼片治疗儿童急性支气管炎的临床效果。方法分析四川大学华西广安医院2014年2月~2016年3月急性支气管炎患儿200例临床资料,患儿依据治疗措施不同进行分组。氨溴索治疗组(治疗A组)100例和氨溴特罗口服溶液联合孟鲁司特钠治疗组(治疗B组)100例。观察两组治疗前后血气分析结果、发热持续时间、咳嗽持续时间、喘息持续时间、肺部啰音持续时间、临床疗效。结果两组患儿治疗前氧分压、二氧化碳分压比较,差异无统计学意义(P>0.05)。两组治疗后氧分压均高于治疗前,二氧化碳分压均低于治疗前,差异有统计学意义(P<0.05);治疗B组治疗后氧分压高于治疗A组,二氧化碳分压低于治疗A组,差异有统计学意义(P<0.05)。治疗B组发热持续时间、咳嗽持续时间、喘息持续时间及肺部啰音持续时间均短于治疗A组,差异有统计学意义(P<0.05)。治疗B组临床治疗总有效率为96%,高于治疗A组的78%,差异有统计学意义(P<0.05)。结论氨溴特罗口服溶液联合孟鲁司特钠咀嚼片治疗急性支气管炎患儿的临床症状改善明显,效果良好,值得临床推广应用。
Objective To explore clinical effect of Ambroxol Hydrochloride and Clenbuterol Hydrochloride Oral Solution combined with Montelukast Sodium Chewable Tablets in the treatment of children with acute bronchitis. Methods Clinical data of 200 children with acute bronchitis in Guang＇an Hospital of West China, Sichuan University from February 2014 to March 2016 were analyzed. Children were grouped according to different treatment measures. Am- broxol treatment group （treatment group A） was 100 cases, Ambroxol Hydrochloride and Clenbuterol Hydroehloride Oral Solution combined with Montelukast Sodium Chewable Tablets group （treatment group B） was 100 cases. The results of blood gas analysis before and after treatment, fever duration, cough duration, asthma duration, pulmonary rales last time, clinical efficacy between two groups were observed. Results Partial pressure of oxygen, carbon dioxide partial pressure between two groups before treatment were compared, with no statistical difference （P 〉 0.05）. Partial pressure of oxygen in two groups after treatment was higher than before treatment, carbon dioxide partial pressure in two groups after treatment was lower than before treatment, with statistical difference （P 〈 0.05）. Partial pressure of oxygen in treatment group B after treatment was higher than in treatment group A, carbon dioxide partial pressure in treatment group B after treatment was lower than in treatment group A, with statistical difference （P 〈 0.05）. Fever duration, cough dura- tion, asthma duration, pulmonary rales last time in treatment group B were shorter than those in treatment group A, with statistical differences （P 〈 0.05）. Total effective rate in treatment group B was 96%, higher than that in treatment group A （78%）, with statistical difference （P 〈 0.05）. Conclusion Clinical symptom improvement of Ambroxol Hydrochloride and Clenbuterol Hydroehloride Oral Solution combined with Montelukast Sodium Chewable Tablets in the treatment of children with acute bronchitis is obviously, the effect is good, it is worthy of clinical promotion and application.
作者
雷玉琳
LEI Yulin(Department of Pediatrics, Guang＇an Hospital of West China, Sichuan University, Sichuan Province, Guang＇an 638000, Chin)
出处
《中国医药导报》
CAS
2017年第6期124-127,共4页
China Medical Herald
关键词
氨溴特罗口服溶液
孟鲁司特钠咀嚼片
儿童
急性支气管炎
Ambroxol Hydrochloride and Clenbuterol Hydroehloride Oral Solution
Montelukast Sodium Chewable Tablets
Children
Acute bronchitis
