摘要
目的 采用屏气试验研究中老年原发性慢性失眠患者颅内大动脉血流储备能力。方法选取年龄在45~60岁无神经系统局灶体征的原发性慢性失眠患者65例为研究对象(慢性失眠组),健康体检者65例(健康对照组)。通过经颅多普勒超声应用屏气试验(breath-holding test)检测每位受试者脑血管储备(cerebrovascular reserve,CVR),对两组结果进行比较分析。结果屏气试验诱发颅内血管血流速度增加。慢性失眠组患者血管储备能力较健康对照组下降,差异有统计学意义(P<0.05)。结论慢性失眠患者呈现颅内血管储备能力下降趋势,提示慢性失眠引起远端脑动脉代偿能力减退,可能是脑血管疾病的危险因素之一。
Objective To study the reserve ability of intracranial large arterial blood flow in the middle-aged and el- derly patients with chronic primary insomnia by breath holding test. Methods A total of 65 patients with primary chron- ic insomnia who were between 45-60 years old and were without local focus in neurological system were selected as study subjects（chronic insomnia group）,and 65 cases of healthy subjects （healthy control group）. The cerebrovaseular reserve was tested by breath holding test via transcranial doppler ultrasonography. The results were compared and ana- lyzed between the two groups. Results The breath holding test induced the increased intracranial blood flow velocity. The blood vessel reserve capacity in the chronic insomnia group was lower than that in the healthy control group, and the difference was statistically significant （P〈0.05）. Conclusion The intracranial vascular reserve capacity is in a de- clining trend in the chronic insomnia patients, suggesting that chronic insomnia may lead to the decrease of distal cerebral artery compensatory capacity, which may be one of the risk factors of eerebrovascular disease.
作者
杨旭
YA NG Xu(Department of No.2 Neurology, Dalian Friendship Hospital in Liaoning Province,Dalian 116001,China)
出处
《中国现代医生》
2017年第4期44-46,共3页
China Modern Doctor
关键词
慢性失眠
脑血管储备
经颅多普勒
屏气试验
Chronic insomnia
Cerebrovascular reserve
Transcranial doppler
Breath holding test
