摘要
目的:探讨分析埃索美拉唑和奥美拉唑治疗胃溃疡的临床效果。方法:选取2012年1月-2016年12月在本院接受治疗的胃溃疡患者98例作为研究对象,按照治疗方法的不同将其分为埃索美拉唑组与奥美拉唑组,每组49例。埃索美拉唑组采用埃索美拉唑治疗,奥美拉唑组采用奥美拉唑治疗,治疗结束后,对比分析两组患者治疗前后的症状评分、溃疡愈合时间、住院时间、治疗效果、Hp变化情况以及不良反应发生率。结果:经过对比发现,埃索美拉唑组患者治疗前的症状评分与奥美拉唑组相比,差异均无统计学意义(P>0.05)。埃索美拉唑组治疗后的症状评分、溃疡愈合时间、住院时间、治疗效果、Hp变化情况以及不良反应发生率与奥美拉唑组比较,差异均有统计学意义(P<0.05)。结论:相对于奥美拉唑来说,埃索美拉唑治疗胃溃疡的临床疗效更加显著,安全性较高,不良反应较少,值得临床推广应用。
Objective： To investigate the clinical effect of Esomeprazole and Omeprazole in the treatment of gastric ulcer.Method： A total of 98 patients with gastric ulcer treated in our hospital from January 2012 to December 2016 were selected and divided into Esomeprazole group and Omeprazole group according to the different treatment methods.Esomeprazole group was treated with Esomeprazole and.Omeprazole group was treated with Omeprazole.After the end of the experiment, the symptom scores, the ulcer healing time, hospital stay, treatment effect, Hp changes and the incidence of adverse reactions of two groups were compared before and after treatment. Result： Compared with Omeprazole group, the symptom score of Esomeprazole group was not significantly different （ P〉0.05 ） .There were significant differences in symptom score, ulcer healing time, hospitalization time, treatment effect, Hp changes and incidence of adverse reactions after treatment of two groups （ P〈0.05 ） . Conclusion： Compared with Omeprazole, Esomeprazole treatment of gastric ulcer clinical efficacy is more significant, higher safety, fewer adverse reactions, it is worthy of clinical application
作者
许国华
张印
XU Guo-hua ZHANG Yin.(Huiyang Sanhe Hospital of Huizhou City, Huizhou 516200, China)
出处
《中国医学创新》
CAS
2017年第8期106-109,共4页
Medical Innovation of China
