摘要
目的分析研讨腹腔镜下腺肌瘤切除术及左炔诺孕酮联合米非司酮药物治疗子宫腺肌病的临床效果。方法病例入选方式为随机抽取法,病例选取范围在该院2014年6月—2016年1月期间收治的子宫腺肌病患者中,共入选90例患者,此90例患者再次依据入院单双顺序分45例对照组和45例研究组,对照组和研究组患者均接受腹腔镜下腺肌瘤切除术和左炔诺孕酮进行治疗,此基础上,研究组再接受米非司酮药物治疗,将两组治疗状况进行对比研讨。结果对比两组患者住院时间、出血量、手术时间等指数,研究组分别为(4.4±2.3)d、(36.9±13.6)m L、(88.5±21.6)min,对照组分别为(4.6±2.0)d、(41.3±14.3)m L、(95.6±16.3)min,研究组和对照组之间数据差异无统计学意义(P>0.05)。对比两组患者术后随访6个月时,Hb、子宫体积、痛经程度、月经天数、月经量,研究组比对照组优,组间数据差异有统计学意义(P<0.05);对比术后随访6个月时,LH、FSH、雌二醇、月经周期等指数,组间数据差异无统计学意义(P>0.05)。结论在治疗子宫腺肌病上,可考虑将腹腔镜下腺肌瘤切除术和左炔诺孕酮,以及米非司酮药物联合使用,此方式疗效突出,可促进子宫恢复,在改善痛经、月经量过多等症状上效果显著,存在较高应用推广价值。
Objective To analyze the clinical effect of laparoscopic adenomyoma removal and levonorgestrel combined with mifepristone in treatment of adenomyosis. Methods 90 cases of patients with adenomyosis admitted and treated in our hospital from June 2014 to January 2016 were selected and divided into two groups with 45 cases in each according to the admission order, and both groups were treated with laparoscopic adenomyoma removal and Levonorgestrel combined with mifepristone, and the research group were treated with mifepristone on this basis and the treatment condition of the two groups was compared and researched. Results The differences in the length of stay, bleeding amount and operation time between the research group and the control group had no statistical significance [4.4±2.3） d,（36.9±13.6） m L,（88.5±21.6） min vs（4.6±2.0）d,（41.3±14.3）m L,（95.6±16.3）min]（P〉0.05）, and after 6-month follow-up, Hb, uterine volume, dysmenorrhea degree, menstruation days and menstruation amount in the research group were better than those in the control group, and the differences between the two groups had statistical significance（P〈0.05）, and the differences in the LH,FSH, estradiol and menstruation cycle had no statistical significance after 6-month follow-up（P〉0.05）. Conclusion We can consider the laparoscopic adenomyoma removal and levonorgestrel combined with mifepristone in treatment of adenomyosis and the curative effect is outstanding, which can promote the rehabilitation of uterus and the effect is obvious in improving the dysmenorrhea and menorrhagia, and it is of higher application and pro-motion value.
出处
《中外医疗》
2017年第4期12-15,共4页
China & Foreign Medical Treatment
