摘要
目的 探究痰热清注射液对慢性阻塞性肺疾病患者肺功能、血气指标以及临床症状改善的影响。方法 选取2010年1月～2013年12月新疆吐哈石油医院收治的90例慢性阻塞性肺疾病患者作为研究对象,按随机数表法将其均分为观察组和对照组,每组各45例。对照组患者接受常规西药治疗,观察组患者在此基础上加用痰热清注射液进行治疗。分别于治疗前、治疗后15d对2组患者的肺功能、血气指标以及各临床症状改善情况进行对比性分析。结果 治疗前,2组患者的第一秒用力呼气容积（FEV1）、用力肺活量（FVC）、第一秒用力呼气容积占用力肺活量比值（FEV_1/FVC）等肺功能指标、动脉血氧分压（PaO_2）、动脉血二氧化碳分压（PaCO_2）、动脉血氧饱和度（SaO2）等血气指标以及各临床症状的计分水平之间比较均差异无统计学意义;治疗后15d,2组患者的FEV_1、FVC、FEV_1/FVC等肺功能指标显著提升,同时其PaO_2、SaO_2水平也出现明显上升,2组患者的PaCO_2水平则有所下降,其各临床症状计分水平也出现明显下降,然而观察组患者的各项指标水平的改善幅度明显大于对照组,差异有统计学意义（P〈0.05）。结论在常规西医治疗的基础上加用痰热清注射液对慢性阻塞性肺疾病进行治疗,能够显著改善其肺功能指标和血气指标水平,各临床症状均得到有效缓解。
Objective To investigate the effect of Tanreqing injection on pulmonary function, blood gas index and clinical symptoms in patients with chronic obstructive pulmonary disease.Methods 90 cases of chronic obstructive pulmonary disease patients from January 2010 to December 2013 in Xinjiang Tuha Petroleum Hospital were selected as the research object.They were randomly divided into the observation group and the control group, 45 cases in each group.The control group received routine western medicine, on the basis of this, the patients in the observation group were treated with Tanreqing injection.Before treatment and 15 days after treatment, compared the two groups of patients with pulmonary function , blood gas index and the improvement of clinical symptoms.Results Before treatment, there were no significant differences between the two groups of patients with FEV1 , FVC, FEV1/FVC and other pulmonary function index, PaO2 , PaCO2 , SaO2 and other blood gas index and the scores of clinical symptoms.15 days after treatment, the two groups of patients with FEV1 , FVC, FEV1/FVC and other indicators of pulmonary function significantly increased, while its PaO2 , SaO2 levels also increased significantly, the level of PaCO2 in the two groups was decreased, and the clinical symptom scores were significantly decreased.However, the improvement rates of the observation group were significantly higher than that of the control group, the differences between the groups were statistically significant （P〈0.05）.Conclusion On the basis of conventional western medicine treatment, add Tanreqing injection to treat chronic obstructive pulmonary disease, can significantly improve the pulmonary function and blood gas index level, the clinical symptoms have been effectively relieved.
出处
《中国生化药物杂志》
CAS
2017年第3期159-161,共3页
Chinese Journal of Biochemical Pharmaceutics
关键词
痰热清注射液
慢性阻塞性肺疾病
肺功能
血气指标
Tanreqing injection
chronic obstructive pulmonary disease
pulmonary function
blood gas index
