摘要
目的:探讨空心加压螺钉内固定术后应用复方骨肽注射液治疗股骨颈骨折的疗效。方法:选取2014年5月—2016年5月南阳市骨科医院收治的股骨颈骨折患者88例作为研究对象,按照随机数字表法分为观察组45例和对照组43例。2组患者均给予空心加压螺钉内固定术,观察组患者术后给予复方骨肽注射液,对照组患者术后给予骨折挫伤胶囊。比较2组患者术后3个月的临床疗效、髋关节功能评分,观察2组患者术前、术后15 d红细胞相关指标变化情况。结果:观察组患者的临床疗效优良率、髋关节功能评分均明显高于对照组,差异均有统计学意义(P<0.05);术后15 d,观察组患者红细胞积聚指数、红细胞电泳指数、红细胞免疫黏附促进因子水平显著高于对照组,差异均有统计学意义(P<0.05)。结论:空心加压螺钉内固定术后应用复方骨肽注射液治疗股骨颈骨折,能有效促进患者骨折愈合,有助于患者髋关节功能的恢复,且对机体红细胞相关指标具有积极的影响。
OBJECTIVE：To probe into the efficacy of compound ossotide injections in treatment of femoral neck fracture after compression screw immobilization. METHODS： 88 cases with femoral neck fracture admitted into Nanyang Orthopaedic Hospital from May 2014 to May 2016 were selected to be divided into observation group and control group via the random number table, with 45 cases in observation group and 43 cases in control group. Two group of patients were treated with compression screw immobilization. And the observation group were given compound ossotide injections, the control group received Guzhecuoshang were compared between two groups after operation, the related capsules. The clinical efficacy, hip joint function scores indicators of red blood cells of two groups were observed before operation and after operation of 15 d. RESULTS： The excellent rate and hip joint function scores of observation group were significantly higher than those of control group, with statistically significant difference （P 〈 0.05 ）. After treatment of 15 d, the level of EAI, EEI and FEER in＇observation group were significantly higher than those of control group, with statistically significant difference（P 〈 0.05）. CONCLUSIONS： Compound ossotide injections in treatment of femoral neck fracture after compression screw immobilization can effectively promote the postoperative fracture healing, helps patients with hip joint function recovery, and has positive effects on the red blood cells indicators.
出处
《中国医院用药评价与分析》
2017年第2期194-196,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
复方骨肽注射液
空心加压螺纹钉内固定
股骨颈骨折
临床疗效
Compound ossotide injections
Compression screw immobilization
Femoral neck fracture
Clinical efficacy
