摘要
明胶酶是基质金属蛋白酶(MMPs)家族的重要组成之一,包括MMP-2和MMP-9,是降解细胞外基质(ECM)的重要酶类。近年研究发现,明胶酶在牙髓炎和根尖周炎发病机制中起重要作用。文章就明胶酶的基础研究及其在牙髓炎和根尖周炎致病、诊断、治疗方面的研究进展做一综述。
Gelatinases are the fundamental components of matrix metalloproteinases,including matrix metalloproteinase-2 and matrix metalloproteinase-9,and have the ability to degrade extracellular matrix.Recent studies have shown that gelatinases play an essential role in the pathogenesis of pulpitis and apical periodontitis.This paper makes a review on recent advances of the basic research of gelatinases and their effects on the pathogenicity,the diagnosis as well as the therapy for pulpitis and apical periodontitis.
出处
《中国实用口腔科杂志》
CAS
2017年第2期108-112,共5页
Chinese Journal of Practical Stomatology
基金
沈阳市科学技术计划(F15-199-1-56)
