摘要
临床价值评估是破解当前中成药(方剂)同品种重复率高、临床定位模糊、适应症宽泛、临床价值不清晰等诸多问题的关键所在。该文简要分析了当前方剂临床价值评估所面临的挑战和机遇,提出了多组学网络背景下的方剂研究策略。通过对中风病类方的比较分析,提示了3个方剂针对中风病不同症状(表型)的特色优势,为临床用药提供参考。多组学网络分析策略为方剂的临床价值评估与比较开辟了新的视角。
Clinical value evaluation is the key issue to solve the problems such as high repetition rate, fuzzy clinical positioning, broad indications and unclear clinical values in Chinese herbal fornmla（ Chinese patent medicine）. By analyzing the challenges and op- portunities of Chinese herbal formula in clinical value evaluation, this paper introduced a strategy of multi-omic network analysis. Through comparative analysis of three stroke treatment formulas, we suggested their different characteristic advantages for variant symp- toms or phenotypes of stroke, which may provide reference for rational clinical choice. Such muhi-omic network analysis strategy may {）pen a unique angle of view for clinical evaluation and comparison of Chinese herbal formula.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2017年第5期848-851,共4页
China Journal of Chinese Materia Medica
基金
国家食品药品监督管理总局课题(CFDA H201501)
关键词
多组学
中药复方
临床价值
网络分析
muhi-omic
Chinese herbal fomaula
clinical value
network analysis
