摘要
目的了解美沙酮维持治疗(MMT)门诊接受治疗的海洛因成瘾者新型毒品滥用情况并分析相关影响因素,为制定美沙酮维持治疗门诊综合干预策略与措施提供依据。方法采用统一问卷对新疆乌鲁木齐市一家美沙酮维持治疗门诊接受治疗的242例海洛因成瘾者进行调查,同时做5项毒品尿代谢物检测。结果 107例自述既往使用过非阿片类的新型毒品,主要是出于好奇心使用并获取新型毒品,主要获得来源于毒友提供和黑市购买;年龄、婚姻状况、民族、新型毒品的认知中对新型毒品成瘾性、危害性、是否会对性行为产生影响、是否会影响美沙酮维持治疗,以及假如别人诱惑你使用新型毒品的态度,与既往使用新型毒品之间存在统计学差异(P<0.05);Logistic回归分析对新型毒品的认知中对新型毒品成瘾性、使用后会对坚持服用美沙酮产生影响、是否会对性行为产生影响3个变量的OR值分别是1.830,1.935和1.778;尿检发现合并使用新型毒品62例,阳性检出率25.62%。结论对毒品的认知、获取途径是促进MMT人群多药滥用的主要原因,加强MMT门诊服务措施及综合干预对减少美沙酮受治者多药滥用有重大意义。
Objective To study and analyze influencing factors of methadone maintenance treatment（MMT） and amphetamine-type stimulants（ATS）, to provide basis for formulating comprehensive measures and strategy of prevention and intervention. Methods Questionnaire survey was carried out in 242 outpatients addicted to opiates or cocaine and treated at MMT clinics. And their urine samples were determined quantitatively. Results Among them, 107 cases used amphetamine-type stimulants before the survey. It was mainly obtained from fellow offering and illegal trade curiosity. There were statistical differences in age, marital status, nationality, acknowledge about drug abuse, harmfulness, influencing sexual beha-vior and methadone maintenance treatment, and attitude to drug abuse, compared with those in previous use（P〈0.05）. Logistic regression analysis showed that OR of three variables of ATS addiction, whether ATC has effects on methadone maintenance treatment response and sexual behavior was 1.830, 1.935 and 1.778, respectively. Urine test indicated that the rate of drug abuse was 25.62%（62 cases）. Conclusions Acknowledge and access to amphetamine-type stimulants are mainly attributable to the drug abuse in MMT outpatients. It is significant to reinforce improvement of service measures at MMT clinics and comprehensive intervention for reducing multi-drug abuse in the outpatients.
作者
李凡
刘雁
李瑞兰
赵燕燕
LI Fan LIU Yan LI Rui-lan ZHAO Yan-yan(The Center for Disease Control and Prevention of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang 830002, Chin)
出处
《疾病预防控制通报》
2017年第1期23-25,30,共4页
Bulletin of Disease Control & Prevention(China)
