摘要
冠心病的主要病理生理基础是动脉粥样硬化。动脉粥样硬化实际上是一种慢性炎症性疾病,在疾病过程中,各种炎性细胞及炎性因子均发挥了重要作用。其中白细胞介素37作为一种新型抗炎因子,可以通过抑制促炎因子的生成等多种途径影响冠心病的疾病进程。研究炎症反应机制和相关炎性因子有望为明确冠心病的病因及进一步的预防和治疗开辟新的途径。
It is well known that atherosclerosis is the pathophysiological basis of coronary heart disease（CHD）. Athero-sclerosis is actually an inflammatory disorder, and lots of inflammatory cells and inflammatory cytokines play important rolesin this process. Interleukin-37, a newly found anti-inflammatory cytokine, is involved in the process of CHD by multiplemechanisms like inhibiting production of proinflammatory factors and so on. The research of the inflammatory reaction mech-anism and the related inflammatory cytokines will open a new way to clarify the etiology and further the prevention as well asthe treatment of CHD.
出处
《医学综述》
2017年第7期1254-1257,1262,共5页
Medical Recapitulate
基金
深圳市科技计划项目(深科技创新[2016]148号)
关键词
冠心病
动脉粥样硬化
炎症
抗炎因子
白细胞介素37
Coronary heart disease
Atherosclerosis
Inflammation
Anti-inflammatory factors
Interleukin-37
