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参松养心胶囊+丹参川芎嗪联合西药治疗冠心病心绞痛随机平行对照研究 被引量:10

Shensong Yangxin capsule(参松养心胶囊) and Salvia Ligustrazine combined with Western Medicine in the Treatment of Angina Pectoris of Coronary Heart Disease a Randomized Controlled Trial
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摘要 [目的]观察参松养心胶囊+丹参川芎嗪联合西药治疗冠心病心绞痛疗效。[方法]使用随机平行对照方法,将100例门诊患者按就诊顺序方法简单随机分为两组,急性发作时舌下含服硝酸甘油。对照组50例单硝酸异山梨脂10~20mg/次,2次/d,口服;阿托伐他汀10~20mg/次,1次/d,口服,阿司匹林肠溶片100mg/次,1次/d,口服;倍他乐克12.5~25mg/次,2次/d,口服。治疗组50例参松养心胶囊4粒/次,3次/d,口服;丹参川芎嗪15m L+250m L生理盐水,1次/d,静滴;西药治疗同对照组。连续治疗14d为1疗程。观测临床症状、心绞痛发作频率、每次发作持续时间、硝酸甘油用量、不良反应。治疗1疗程(14d),判定疗效。[结果]治疗组显效17例,有效18例,无效15例,总有效率96.00%;对照组显效20例,有效28例,无效2例,总有效率70.00%;治疗组疗效优于对照组(P<0.01)。[结论]参松养心胶囊+丹参川芎嗪联合西药治疗冠心病心绞痛,疗效满意,无严重不良反应,值得推广。 [Objective] To observe Shensong Yangxin capsule and salvia miltiorrhiza ligustrazine combined with western medicine in the treatment of coronary heart disease with angina pectoris. [Methods] 100 outpatients were randomly divided into two groups according to the method of random parallel control. The control group of 50 cases of isosorbide grease 10~20 mg/times, 2 times/d, oral; atorvastatin 10~20 mg/times, 1 times/d, oral, aspirin enteric-coated tablets 100 mg/times, 1 times/d, oral betaloc; 12.5~25 mg/times, 2 times /d, oral. The treatment group of 50 cases of Shensong Yangxin capsule 4 pills/time, 3 times/d, oral; salvia miltiorrhiza ligustrazine 15 m L+250m L saline, 1/d, intravenous drip; western medicine treatment with the control group. Continuous treatment for 1 courses of 14 d. Observation of clinical symptoms, angina attack frequency, duration of each attack, dosage of nitroglycerin, adverse reactions. Treatment of 1 courses of treatment(14d), determine the efficacy. [Result] 17 cases were markedly effective, 18 cases were effective, 15 cases were ineffective, the total effective rate was 96%; the control group was 20 cases, 28 cases were effective, 2 cases ineffective, the total effective rate was 70%. The treatment group was better than the control group(P〈0.01). [Conclusion] Shensong Yangxin capsule and salvia ligustrazine combined with western medicine in the treatment of angina pectoris of coronary heart disease, the curative effect is satisfied, no serious adverse reactions, worthy of promotion.
作者 马明玉
出处 《实用中医内科杂志》 2017年第2期37-39,共3页 Journal of Practical Traditional Chinese Internal Medicine
关键词 冠心病心绞痛 参松养心胶囊 硝酸甘油 单硝酸异山梨脂 阿托伐他汀 阿司匹林肠溶片 倍他乐克 心绞痛发作频率 每次发作持续时间 硝酸甘油用量 中西医结合治疗 随机平行对照研究 coronary heart disease angina pectoris Shensong Yangxin capsule nitroglycerin(参松养心胶囊) isosorbide grease atorvastatin aspirin enteric-coated tablets metoprolol angina frequency duration of each episode the dosage of nitroglycerin combination therapy randomized controlled study
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