摘要
目的 分析变温试验优势偏向（directional preponderance, DP）与自发性眼震（spontaneous nystagmus, SN）和前庭觉障碍的相关性，明确DP与外周性眩晕患者疾病所处时期的关系，探讨其在前庭功能评估中的意义。方法 收集2012年3月至2014年6月于复旦大学附属眼耳鼻喉科医院门诊就诊的外周性眩晕患者394例，比较动静态姿态平衡台感觉结构以及视频眼震电图（videonystagmography, VNG）测试中SN、半规管功能减弱（unilateral weakness, UW）及DP的结果，并进行统计学分析。结果 在变温试验中，有SN和DP的患者其末次眩晕发作时间与检查相距的时间分别平均为4.4 d和7.3 d，而无SN和DP的患者平均时间分别为18.3 d和17.5 d。根据是否存在DP，将患者分为两组，其中DP组203例、无DP组191例。比较两组SN的发生率，DP组21.67%（44/203）、无DP组2.09%（4/191），差异具有统计学意义（χ2＝35.27，P＝0.000）。在DP组中，动静态姿态平衡台感觉结构测试提示前庭功能不足者165例（81.28%），无DP组中前庭功能不足者123例（64.40%），组间差异具有统计学意义（χ2＝14.26，P＝0.000）。结论 变温试验DP阳性患者更易发生SN和前庭觉不足导致的平衡障碍；DP可能和SN一样，与外周性眩晕患者疾病所处的发作时期有关。
Objective To analyze the relationship between directional preponderance （DP）, spontaneous nystagmus（SN） and vestibular disorders, and to investigate the significance of DP in directing peripheral vestibular function in patients with vertigo.Methods This was a retrospective analysis of 394 cases diagnosed with peripheral vestibular disease accompanied by vertigo from March 2012 to June 2014 in the Outpatient Department of the Eye ＆ ENT Hospital of Fudan University. Results of static and dynamic posture equilibrium tests, SN, unilateral weakness（UW）, and DP in videonystagmography（VNG） were analyzed and compared.Results The mean interval time between the last vertigo attack and examination in patients with SN or DP in caloric test were 4.4 d and 7.3 d respectively, and those without SN or DP were 18.3 d and 17.5 d respectively. The patients were divided into two groups according to DP results of caloric test. DP-normal group had 203 cases and DP-abnormal group had 191 cases. Spontaneous nystagmus was presented in 44 cases in the DP-normal group （21.67%） and four in the DP-abnormal group （2.09%）. A significant difference was found between the two groups （χ2=35.27, P=0.000）. Deficiency of vestibular function was noted in 165 cases in the DP-normal group （81.28%） and 123 （64.40%） in the DP-abnormal group in static and dynamic posture equilibrium tests. The difference between the two groups was statistically significant （χ2=14.26, P=0.000）.Conclusion Compared with DP-normal patients, DP-abnormal patients are more likely to have spontaneous nystagmus and balance disorders due to vestibular dysfunction.
出处
《中华耳鼻咽喉头颈外科杂志》
CAS
CSCD
北大核心
2017年第3期200-204,共5页
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
基金
国家自然科学基金（青年科学基金项目）（81200739）
关键词
眩晕
前庭功能试验
冷热试验
眼震电图描记术
Vertigo
Vestibular function tests
Caloric tests
Electronystagmography
