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甲状腺结节良恶性的多因素分析预测 被引量:1

Multivariate Analysis and Prediction of Benign and Malignant Thyroid Nodules
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摘要 目的:采用多因素分析的方法预测甲状腺结节良恶性。方法:选取2014年9月~2016年9月在某院接受医治的180例甲状腺结节已行甲状腺切除术的患者为对象,对所有患者的患病资料进行系统的分析,探究甲状腺结节良恶性的影响因素。结果:恶性患者的结节直径明显小于良性患者(P<0.05),且血浆中甲状腺球蛋白抗体(thyroglobulin antibodies,TgAb)浓度和促甲状腺激素(thyroid stimulatinghormone,TSH)浓度明显高于良性患者(P<0.05)。而血浆中胆固醇、低密度脂蛋白、高密度脂蛋白、T3及T4的浓度在良恶性结节患者体内没有显著差异(P>0.05)。结论:甲状腺结节的良恶性与患者甲状腺结节直径大小、血浆中TgAb及TSH的浓度有关联,与血浆中胆固醇、低密度脂蛋白、高密度脂蛋白、T3及T4的浓度并无相关性。 Objective:To predict the benign and malignant thyroid nodules by multivariate analysis.Methods:180cases of patients with thyroid nodules treated with thyroidectomy in a hospital from September 2014 to September 2016 were selected as the objects.The disease data of all patients was systematically analyzed and the influencing factors of benign and malignant thyroid nodules were explored.Results:The diameter of nodules of patients with malignant tumor was significantly smaller than that of patients with benign tumor(P〈0.05).The concentrations of thyroglobulin antibodies(TgAb)and thyroid stimulatinghormone(TSH)in plasma of patients with malignant tumor were significantly higher than those of patients with benign tumor(P〈0.05).There was no significant difference in concentrations of cholesterol,low density lipoprotein,high density lipoprotein,T3 and T4in patients with benign and malignant nodules(P〉0.05).Conclusion:The benign and malignant thyroid nodules are associated with the diameter of nodules and the concentrations of TgAb and TSH in plasma in patients,but are not associated with concentrations of cholesterol,low density lipoprotein,high density lipoprotein,T3 and T4in plasma in patients.
作者 高勇
出处 《数理医药学杂志》 2017年第4期501-503,共3页 Journal of Mathematical Medicine
关键词 甲状腺结节 良恶性 多因素分析 预测 thyroid nodule benign and malignant multiple factors analysis prediction
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