摘要
目的:系统评价中医药对高血压前期血压的影响。方法:计算机检索国内外关于中医药干预高血压前期的临床随机对照试验,使用I^2评估各研究之间的异质性,并用Rev Man 5.2.0软件进行Meta分析。结果:共纳入8篇文献,1005例受试者。Meta分析结果提示,与对照组相比,试验组在降低收缩压(WMD:-3.65;95%CI:-5.35^-1.94;I^2∶87%)及舒张压(WMD:-2.58;95%CI:-4.30^-0.86;I^2∶93%)方面均优于对照组,2组间的差异具有统计学意义(P<0.01)。结论:在生活方式干预的基础上,加用中医药干预有助于进一步降低血压水平。
Objective：To evaluate the effect of Chinese herbal medicine on blood pressure in pre-hypertensive cases. Methods： Domestic and international databases were searched for relevant randomized controlled trials（RCTs） which investigated the effect of Chinese herbal medicine on blood pressure in pre-hypertensive cases. Heterogeneity of cross-studies was assessed, using 12. All recta-analyses were condueted through RevMan 5. 2. 0. Results：Eight RCTs involving 1005 subjects were selected. Meta-analysis demonstrated that the test group reduces the level of both systolic blood pressure （ WMD： - 3.65 ; 95 % CI： - 5.35 ~ - 1.94; P 〈 0. 01, 12：87% ）and diastolic blood pressure（WMD： -2. 58; 95%CI： -4. 30 ~ -0. 86;P 〈0. 01 ; 12：93% ）,eompared with the control group. The difference was statistically significant. Conclusion：Basing on lifestyle intervention, Chinese herbal medicine helped reducing the level of blood pressure.
出处
《世界中医药》
CAS
2016年第11期2441-2443,2449,共4页
World Chinese Medicine
基金
湖北省教育厅自然科学研究计划项目(编号:B2013169)
宜昌市医疗卫生科研项目(编号:A15301-33)
关键词
中草药
高血压前期
META分析
Chinese herbal medicine
Pre-hypertension
Meta-analysis
