摘要
目的探讨血液透析联合血液灌流对尿毒症患者β_2-微球蛋白(β_2-MG)和超敏C反应蛋白(hs-CRP)的影响。方法选取50例尿毒症患者,随机分为观察组和对照组。对照组采用单纯血液透析治疗,观察组使用血液透析联合血液灌流治疗。首次治疗后和治疗2个月后检查患者β_2-MG和hs-CRP水平。结果观察组首次治疗后、治疗2个月后β_2-MG、hs-CRP水平较治疗前显著降低(P<0.05),且β_2-MG、hs-CRP水平显著低于对照组(P<0.05)。结论血液透析联合血液灌流可降低尿毒症患者β_2-MG和hs-CRP浓度。
Objective To explore the effects of hemodialysis combined with hemoperfusion on the expression of β2-microglobulin（β2-MG） and high-sensitivity C-reactive protein（hs-CRP） in patients with uremia.Methods A total of 50 patients with uremia were randomly divided into control group and observation group.The control group was treated by single hemodialysis,while the observation group was treated by hemodialysis combined with hemoperfusion.After the first treatment and 2months after treatment,the levels of β2-MG and hs-CRP were detected.Results After the first treatment and 2 months after treatment,the levels of β2-MG and hs-CRP in the observation group were significantly lower than those before treatment,and were significantly lower than those in the control group（P〈0.05）.Conclusion Hemodialysis combined with hemoperfusion can reduce the levels of β2-MG and hs-CRP in patients with uremia.
出处
《实用临床医药杂志》
CAS
2017年第5期65-67,共3页
Journal of Clinical Medicine in Practice
