摘要
采用水热合成法制备了镁掺杂羟基磷灰石,研究了不同Mg掺杂含量对羟基磷灰石生物活性的影响.对镁掺杂羟基磷灰石的物相成分、元素组成、官能团以及SBF浸泡后的形貌进行了表征.结果表明,镁的掺杂可以极大地提高羟基磷灰石的生物活性,当钙镁的理论原子比达到1∶1时,样品表面生成了大量的磷灰石,随着镁含量的增大,镁掺杂羟基磷灰石的生物活性随之提高.镁掺杂羟基磷灰石的研究为人工骨材料的临床应用奠定理论和应用基础.
Magnesium doped hydroxyapatite was prepared by hydrothermal synthesis method,and the effect of doping different content of magnesium on the hydroxyapatite biological activity was studied.The phase composition,element composition,functional group and morphology after SBF soaked of magnesium doped hydroxyapatite were characterized.The results show that magnesium doping can greatly improve the biological activity of hydroxyapatite.When the theory of calcium and magnesium atom ratio reached 1 ∶ 1,a large amount of apatite was formed on the sample surface,and with the increase of magnerium content,the biological activity of magnesium doped hydroxyapatite is improved.The study of Mg doped hydroxyapatite build the foundation of theory and application for the clinical application of artificial bone materials.
出处
《陕西科技大学学报（自然科学版）》
2017年第2期61-65,共5页
Journal of Shaanxi University of Science & Technology
基金
国家自然科学基金项目(51072107)
陕西省科技厅自然科学基金项目(2014JM6233)
陕西省大学生创新创业训练计划项目(1349)
陕西科技大学学术骨干培育计划项目(XSGP 201208)
陕西科技大学博士科研启动基金项目(BJ13-09)
陕西科技大学校级大学生创新创业训练计划项目(025)
