摘要
目的探讨老年住院患者社区获得性肺炎病原菌分布与耐药性。方法方便选取该院103例老年社区获得性肺炎患者为研究对象,将其合格痰标本进行药敏试验及痰培养,对病原菌分布及耐药性进行分析。结果 103例老年社区获得性肺炎患者共分离出致病菌130株,革兰阴性菌73株,占56.15%,前3位分别为铜绿假单胞菌、大肠埃希菌与肺炎克雷伯菌;革兰阳性菌57株,占43.85%,前3位分别为金黄色葡萄球菌、肺炎链球菌与溶血性链球菌。药敏实验结果显示,革兰阴性菌对头孢吡肟、左旋氧氟沙星、哌拉西林/他唑巴坦、多粘霉素、阿米卡星、亚胺培南的耐药性较低;革兰阳性菌对万古霉素、呋喃妥因、替考拉宁、甲氧苄氨嘧啶、复方磺胺等耐药性较低。结论该院老年社区获得性肺炎患者以革兰阴性菌为主,且大多耐药程度高,通过病原菌耐药性监测,可提高临床用药合理性。
Objective To discuss the distribution and tolerance of community acquired pneumonia pathogenic bacteria in senile inpatients. Methods Convenient selection 103 cases of senile patients with community acquired pneumonia in our hospital were selected as the research objects and the qualified sputum specimens were given the drug sensitive test and culture, and the distribution and tolerance of pathogenic bacteria were analyzed. Results In the 103 cases of senile patients with community acquired pneumonia, 130 strains of pathogenic bacteria were isolated, including 73 strains of gram-negative bacteria, accounting for 56.15%, and top three were respectively pseudomonas aeruginosa, E.coli and klebsiella pneumonia,and 57 strains of gram-positive bacteria, accounting for 43.85%, and the top three were respectively staphylococcus aureus,streptococcus pneumoniae and streptococcus hemolyticus, and the drug sensitive experimental results showed that the tolerance of gram-negative bacteria to cefepime, levofloxacin, piperacillin/tazobactam, polymyxin, Amikacin and imipenem was lower, and the tolerance of gram-positive bacteria to vancomycin, nitrofurantoin, teicoplanin, trimethoprim and sulfamethoxazole was lower. Conclusion In our hospital, the senile patients with community acquired pneumonia is mainly gram-negative bacteria, and the tolerance degree of most bacteria is high, and the tolerance monitoring of pathogenic bacteria can improve the clinical medication rationality.
出处
《中外医疗》
2017年第5期11-13,17,共4页
China & Foreign Medical Treatment
关键词
社区获得性肺炎
老年住院患者
病原菌
耐药性
Community acquired pneumonia
Senile inpatients
Pathogenic bacteria
Tolerance
