摘要
目的:分析P63在子宫内膜腺癌发生发展中的表达及意义。方法:采用免疫组织化学SP法对P63在33例子宫内膜腺癌、10例正常增生期子宫内膜的表达情况进行分析,比较两组的阳性率。结果:子宫内膜癌组P63的表达阳性率明显高于正常增生期子宫内膜组(P<0.05)。子宫内膜癌组中,肌层浸润≥1/2的P63表达阳性率明显高于肌层浸润<1/2(P<0.05)。结论:P63的阳性表达随着子宫内膜样腺癌的浸润深度增加,侵袭性增加。
Objective：To investigate the expression and significance of P63 in the occurrence and development of endometrial adenocarcinoma.Methods：Immunohistochemical SP method was used to analyze the expression of P63 in 33 cases of endometrial adenocarcinoma and 10 cases of normal proliferative endometrium.The positive rates of the two groups were compared.Results：The positive rate of P63 expression in endometrial carcinoma group was significantly higher than that in normal proliferative endometrium group（P〈0.05）.Endometrial carcinoma group,myometrial invasion was 1/2 positive expression rate of P63 was significantly higher than that in muscle invasive 1/2（P0.05）.Conclusion：The positive expression of P63 increased with the infiltration depth of endometrioid adenocarcinoma.
出处
《中国医药导刊》
2017年第3期251-251,253,共2页
Chinese Journal of Medicinal Guide
