摘要
目的:探究HBP对脓毒症相关急性呼吸窘迫综合征患者预后的影响。方法:选择100例脓毒症相关性急性呼吸窘迫综合征患者作为研究对象,根据是否患有高血压(HBP)分为观察组50例和对照组50例,观察组患者合并有HBP,对照组不合并HBP。观察治疗1个月后两组患者的预后情况。结果:经过1个月治疗,两组患者的氧合指数、APACHEⅡ评分和SOFA评分结果对比,观察组患者的SOFA评分为(6.3±2.8)分,APACHEⅡ评分为(16.8±5.2)分,显著高于对照组的(4.1±4.3)分和(12.7±8.3)分,而观察组的氧合指数仅为253.9±43.4,明显低于对照组的285.7±32.4,两组比较具有统计学意义(P<0.05);观察组患者中的急性肺炎、急性支气管炎、咽喉感染以及慢性继发感染的发病率均高于对照组,两组比较差异均有统计学意义(P<0.05);观察组患者Vmax50为(3.12±0.48)L/s、Vmax75为(4.92±0.75)以及Vmax25为(1.19±0.31)L/s,均低于对照组,两组比较差异具有统计学意义(P<0.05)。结论:高血压会对脓毒症相关急性呼吸窘迫症患者的肺功能间接或者直接造成损伤,因此控制高血压可有效改善患者的预后情况。
Objective To explore the effect of HBP on the prognosis of patients with acute respiratory distress syndrome associated with sepsis.Method 100 cases of sepsis correlations in patients with acute respiratory distress syndrome were selected as the research object,according to whether suffering from high blood pressure（ HBP） they were divided into observation group 50 cases and control group 50 cases,observation group of patients with HBP,control group not combined HBP.Observation of treatment after a month of two groups of patients prognosis.Results After one month treatment,two groups of patients oxygenation index,APACHE Ⅱ grade and SOFA,the results of observation group of patients with SOFA score was（6.3 ± 2.8）,APACHE Ⅱscore was（16.8 ± 5.2）,significantly higher than（4.1 ± 4.3） and（12.7 ± 8.3） of control group,the observation group of oxygenation index only 253.9 ± 43.4,significantly lower than 285.7 ± 32.4 in the control group,comparing the two groups there was statistically significant difference（ P 0.05）;In the observation group of patients with acute pneumonia,acute bronchitis,throat infection were chronic secondary infection rates are higher than the control group,comparing the two groups there was statistically significant difference（ P 0.05）;Observation group of patients,Vmax50 was（3.12 ± 0.48） L/s,Vmax75 was（4.92± 0.75） L/s,and Vmax25 was（1.19 ± 0.31） L/s,which was lower than the control group,comparing the two groups there was statistically significant difference（P〈0.05）.Conclusion High blood pressure will be related to sepsis of pulmonary function in patients with acute respiratory distress syndrome indirectly or directly cause damage,so the effective control of hypertension can improve the prognosis of patients.
出处
《吉林医学》
CAS
2017年第4期618-621,共4页
Jilin Medical Journal
关键词
高血压
脓毒症
急性呼吸窘迫综合征
Hypertension
Sepsis
Acute respiratory distress syndrome
