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卒中后抑郁的相关因素研究 被引量:5

Study on related factors in patients with post-stroke depression
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摘要 目的分析卒中后抑郁(PSD)的发生率、相关因素及相关度。方法对68例急性脑卒中患者,采用自制一般情况调查表、Zung抑郁自评量表(SDS)、汉密尔顿抑郁量表(HAMD)、简易精神状态量表(MMSE)、斯堪的纳维亚卒中量表(SSS)、美国国立卫生研究院卒中量表(NIHSS)、Barthel Index(BI)评分和改良的Rankin量表(mRS)评分,并用逐步Logistic回归统计方法对各相关因素进行分析。结果脑卒中发病2周时伴发PSD的发生率为32.4%,其中轻度抑郁27.9%,中度抑郁2.9%,重度抑郁1.5%;离异或丧偶、独自居住、性格内向,脑卒中病灶数量多、面积大,伴随冠心病及高C-反应蛋白,神经功能缺损程度高、日常生活能力差的患者,发生PSD的可能性更大。结论卒中后抑郁在脑卒中患者中较为常见,以轻中度为主,是生物、心理和社会因素共同作用的结果。 Objective To analyze the incidence of post - stroke depression ( PSD) and its related factors. Methods Sixty - eight pa-tients with acute stroke were assessed by self - designed questionnaire, Zung Self - Rating Depression Scale ( SDS) , Hamiton Depression Rating Scale ( HAMD) , Mini - Mental State Examination ( MMSE) , Scandinavian Stroke Scale ( SSS) , National Institutes of Health Stroke Scale ( NIH- SS) , Barthel Index (BI) and Modified Rankin Scale (mRS). A multiple factor analysis with logistic regression method was carried out to analyze all related factors in these data. Results The incidence of PSD was 32. 4% , including 27. 9% mild patients, 2. 9% moderate patients and 1.5% severe patients. Patients had been divorced, lost spouse or live alone had an introvert nature, numerous or large lesions, associated with coronary artery disease or high level of CRP, neurological deficits or disability had higher possibility for PSD. Conclusion PSD is a common complication with many related factors after stroke, the most of PSD in patients are mild and moderate, and this kind of disease may be caused by biological - psychological and social factors.
出处 《临床和实验医学杂志》 2017年第8期818-820,共3页 Journal of Clinical and Experimental Medicine
关键词 卒中后抑郁 发生率 相关因素 Post - stroke depression Incidence Related factors
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