摘要
目的观察雾化吸入布地奈德(普米克令舒)治疗小儿急性感染性喉炎的临床效果以及安全性。方法选取2015年3月-2016年10月医院收治的小儿急性感染性喉炎患者96例,随机分为观察组和对照组各48例。观察组患者在常规治疗基础上给予普米克令舒雾化吸入;对照组患者在常规治疗基础上给予氢化可的松琥珀酸钠静脉滴注。统计2组患者治疗效果、临床表现消失时间及不良反应发生情况。结果观察组患儿显效率和总有效率分别为45.83%和83.33%高于对照组的31.25%和62.50%,差异均有统计学意义(P<0.05)。观察组患儿发热、犬吠样咳嗽、吸气时哮鸣音、声嘶及吸气性呼吸困难等症状消失时间均明显短于对照组,差异均有统计学意义(P<0.05)。2组患者均无明显不良反应发生。结论雾化吸入普米克令舒治疗小儿急性感染性喉炎可取得较好效果,患儿的治疗有效率得以提高,治疗时间缩短,在缓解患儿病痛的同时也容易被患儿家属所理解和接受,具有重要的临床意义。
Objective To observe the clinical efficacy and safety of budesonide（ pulmicort） inhalation therapy in treatment of children with acute infectious laryngitis. Methods 96 children with acute infectious laryngitis from March 2015 to October 2016 in hospital were randomly divided into observation group and control group,with 48 cases in each group. On the basis of conventional treatment,observation group was given pulmicort aerosol inhalation; control group was given hydrocortisone sodium succinate to pine vein infusion. Treatment effect,clinical manifestations of disappearance time and adverse reactions between two groups were compared. Results The significant efficiency and total efficiency of observation group were 45. 83%and 83. 33% respectively,and the control group were 31. 25% and 62. 50% respectively. The significant efficiency and total efficiency of observation group were higher than that of control group（ P〈0. 05）. Fever,barking cough,inspiratory wheeze and hoarseness disappeared time were all shorter than control group,the differences were statistically significant（ P〈0. 05）. There was no obvious adverse reaction in two groups. Conclusion Pulmicort inhalation in treatment of children with acute infectious laryngitis can achieve better results,with the effective rate of treatment can be improved,shorter treatment time,relieve pain in children is also easy to be understood and accepted by the families of the children,and has important clinical significance.
出处
《临床合理用药杂志》
2017年第7期38-39,共2页
Chinese Journal of Clinical Rational Drug Use
