摘要
目的研究皮肤组织光学特性参数对光子传输的影响。方法根据皮肤组织的结构,构建五层皮肤组织模型。利用蒙特卡罗方法模拟无限细光束在皮肤组织中的传输,逐层改变各光学特性参数,比较吸收能量密度、光能流率、漫反射率的变化。结果增大某一层吸收系数,该层皮肤组织的吸收能量密度增大,光能流率降低,浅层漫反射率略有减小,三者衰减梯度均增大;减小某一层散射系数或增大该层各向异性因子,吸收能量密度减小,吸收能量密度和光能流率的衰减梯度均明显减小;浅层漫反射率略有减小,衰减梯度增大;改变越深层皮肤的光学特性参数对光子传输的影响越小。结论漫反射率受各光学特性参数变化影响较小,吸收能量密度和光能流率则有较明显改变。
Objective To investigate the influence of optical parameters on photon transmission in skin tissues. Methods Skin tissues have complex multilayer structures. It is of great significance to study the light distribution in the tissue for bio- medical diagnosis and treatment. A skin tissue model was constructed based on the structure of skin tissueand Monte Carlo method was adopted to simulate the transmission of infinite thin beam in the skin tissue. At the same time, the parameter of each optical character- istic was changed layer by layer so as to compare the changes of the absorption energy density, fluence rate and diffuse reflectance. Results When the absorption coefficient of a layer was increased, the absorption energy density of the skin tissue increased, fluence ratedecreased, the shallow diffuse reflectance droppedslightly and the attenuation gradient of the three indicators rose. When the scat- tering coefficient was reduced or the anisotropy factors increased, the absorption energy density decreased, the attenuation gradient of the absorption energy density and the fluence rate dropped obviously, the shallow diffuse reflectance decreasedslightly and the attenua- tion gradient increased. The deeper the layer of skin of which the optical properties were changed, the smaller the influence on the pho- ton transmission. Conclusions The influence of changes to optical parameters was slight on diffuse reflectance, but that on absorption energy density and fluence was obvious.
出处
《中国激光医学杂志》
CAS
2017年第1期7-11,56,57,共7页
Chinese Journal of Laser Medicine & Surgery
基金
福建省教育厅项目(JA11205)
现代精密测量与激光无损检测福建省高校重点实验室开放课题(s20150504)
关键词
组织光学
蒙特卡罗模拟
吸收能量密度
光能流率
漫反射率
Tissue optics
Monte Carlo Simulation
Absorption energy density
Fuence rate
Diffuse reflectance
