摘要
目的观察胞磷胆碱治疗血管性帕金森综合征患者认知障碍的临床疗效。方法将80例血管性帕金森综合征(VP)且伴有认知障碍的患者随机分为观察组与对照组,观察组服用胞磷胆碱治疗,比较两组患者治疗前及治疗后1月、3月、6月的MMSE、Mo CA量表评分。结果观察组患者治疗后1月、3月、6月的MMSE、Mo CA量表评分均高于对照组,且随着治疗时间延长而增高。观察组治疗后3月、6月的评分明显高于对照组(P<0.05)。结论胞磷胆碱能显著改善VP患者的认知功能障碍。
Objective To observe the efficacy of citicoline in treatment of vascular parkinsonism patients with cognition disorders.Methods Eighty vascular parkinsonism patients with cognition disorders were randomly divided into observation group and control group.Patients in observation group were given citicoline.The MMSE score and Mo CA score before and after treatment in January,March and June were compared.Results MMSE score and Mo CA score of observation group before and after treatment in January,March and June were higher than that of control group,respectively,and above score increased with the treatment time.There was a statistically significant difference in score after treatment for March and June（P〈0.05）.Conclusion Citicoline significantly improve cognition disorders in patients with vascular parkinsonism.
出处
《延安大学学报（医学科学版）》
2017年第1期24-25,38,共3页
Journal of Yan'an University:Medical Science Edition
