摘要
为了减少异丙酚诱导麻醉用量的同时,达到相应的诱导麻醉效果,试验选用地西泮配合异丙酚进行诱导麻醉。通过对地西泮-异丙酚不同剂量搭配的筛选,观察相应的麻醉时间、生物反射及其对犬循环与呼吸系统的影响。结果显示其麻醉时间比单独异丙酚诱导麻醉明显延长,并随着地西泮和异丙酚剂量的增加其麻醉时间明显延长。试验中以0.4 mg/kg地西泮配合异丙酚时,麻醉效果显著,麻醉时间比单独使用异丙酚延长9.25±2.37 min,苏醒时间延长8.82±2.90 min。因此,以0.4 mg/kg地西泮分别配合3.5mg/kg、5mg/kg或7mg/kg剂量的异丙酚复合诱导麻醉是本次试验的最佳搭配剂量,可作为犬诱导麻醉的可选方法之一。
In order to reduce the dose of propofol and reach the relative anesthetic effect in the process of the induction anesthesia, the induction of anesthesia is carried Qut using the diazepam accompanied with propofol. Having the different collocation doses of dia- zepam and propofol, and then to observe the corresponding duration of anesthesia and its impact on the canine＇s biological reflection and circulation and respiratory system. The experiment shows that the anesthesia duration of the compound＇s is obviously longer than the alone - propofol anesthesia method. Also, with diazepam and propofol dose increased, its anesthesia time is also much longer. In the experiments, the 0.4 mg / kg diazepam coupled with propofol makes the best anesthesia effect , the duration of compound anes- thesia extends 9.25 ± 2.37 min than propofol＇s , and the recovery time prolonged 8.82 ± 2.90 min. Therefore, 0.4 mg/kg, respec- tively, with diazepam 3.5mg / kg, 5mg / kg or 7mg / kg dose of propofol combined with induction of anesthesia is the best dose of this trial, this is one of the alternative methods of inducing anesthesia on canine.
出处
《内蒙古农业大学学报（自然科学版）》
CAS
2017年第1期1-8,共8页
Journal of Inner Mongolia Agricultural University(Natural Science Edition)
关键词
异丙酚
地西泮
诱导麻醉
剂量搭配
麻醉监测
Propofol
diazepam
induction of anesthesia
dose collocation
anesthesia monitoring
