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宫颈锥切术后切缘与病变残留的关系 被引量:12

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摘要 目的探讨宫颈锥切术后切缘与病变残留的关系,为宫颈锥切术后进一步治疗提供临床参考。方法收集经宫颈活检诊断为高级别宫颈上皮内瘤样病变(CIN)和微小浸润癌首次接受宫颈锥切术及术后补充行二次手术的69例患者临床资料并进行回顾性分析,对患者年龄、孕产次、绝经、腺体是否累及、锥切方式、补充手术方式、切缘与补充手术标本残留病变作单因素和多因素分析。结果 69例患者年龄(47.28±8.28)岁;CIN2级4例,CIN3级61例,早期浸润癌4例;切缘阴性27例,切缘阳性42例,其中内切缘阳性13例。单因素分析结果:切缘阳性病例病变残留率50.0%(21/42)高于切缘阴性病例病变残留率33.3%(9/27),但差异无统计学意义(P>0.05);内切缘阳性病例病变残留率69.2%(9/13)明显高于其他切缘病例病变残留率37.5%(21/56),差异有统计学意义(P<0.05)。多因素分析显示:内切缘阳性为病变残留的高危因素,OR=1.322(95%CI:1.026~13.706,P<0.05)。结论切缘阳性和切缘阴性病例中均存在部分病变残留,其中内切缘阳性的病例高度提示病变残留可能,应考虑补充二次手术。
出处 《中国妇幼保健》 CAS 2017年第7期1446-1449,共4页 Maternal and Child Health Care of China
基金 温州市科学技术局课题项目(y20160334)
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