摘要
目的了解口腔颌面部医院感染患者不同部位病原菌分布与耐药性,为合理使用抗菌药物和降低医院感染率提供参考依据。方法回顾性分析2010-2016年口腔颌面外科40 077例患者的临床资料,采用API鉴定系统进行病原菌鉴定,采用纸片扩散K-B法,进行药物敏感性试验,并对其结果进行统计分析。结果有395例发生医院感染,感染率为0.99%;手术部位感染和肺部感染均以革兰阴性菌为主,分别为168株、150株,分别占70.59%、89.82%;不同感染部位病原菌耐药率基本一致。结论口腔颌面外科术后感染患者的病原菌以革兰阴性菌为主,铜绿假单胞菌是主要病原菌,临床医师应根据药敏试验合理选择抗菌药物,从而减低医院感染率。
OBJECTIVE To investigate the distribution and drug resistance of pathogenic bacteria in different sites in patients with oral and maxillofacial region nosocomial infections, so as to provide references for rational use of an- timicrobial drugs and reducing nosocomial infection rates. METHODS Clinical data of 40077 cases of patients from oral and maxillofacial surgery from Jan. 2010 to Dec. 2016 were retrospectively analyzed. Pathogenic bacteria were identified by API and drug sensitivity test was performed by K-B agar disk diffusion method. The results were statistically analyzed. RESULTS There were 395 cases of patients occurred nosocomial infections, with the infection rate of 0. 99 %. The pathogenic bacteria of surgical site infection and pulmonary infection were mainly gram-negative bacteria, which were 168 strains and 150 strains, accounting for 70.59% and 89.82%, respective- ly. The infection rates of pathogens in different infection sites were basically the same. CONCLUSION Most of the bacteria of postoperative nosocomial infections in oral and maxillofacial surgery were gram-negative bacteria. Pseudornonas aeruginosa was the main pathogen. Clinicians should select appropriate antibiotics according to the drug sensitivity test, so as to reduce the nosocomial infection rate.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2017年第8期1821-1824,共4页
Chinese Journal of Nosocomiology
基金
北京大学口腔医院院青年科研基金资助项目(PKUSS20130207)
北京大学口腔医院临床新技术新疗法资助项目(PKUSSNCT-12A11)
关键词
医院感染
口腔颌面外科
病原菌
耐药性
Nosocomial infection
Oral and maxillofacial surgery
Pathogenic bacteria
Drug resistance
