摘要
目的系统评价电针对三叉神经痛的有效性和安全性。方法计算机检索CNKI、WanFangData、VIP、CBM、PubMed、EMbase和The Cochrane Library,查找电针治疗三叉神经痛的随机对照研究试验,检索时限自1996年3月至2016年3月。由2位研究者独立地按照纳入与排除标准筛选文献、提取资料,然后采用Cochrane风险偏倚评估工具对纳入文献进行偏倚风险评估。采用RevMan5.3软件进行Meta分析。结果最终纳入12篇文献,共847例受试者。Meta分析结果显示,在提高治疗总有效率[OR=4.04,95%CI(2.67,6.13),P<0.00001]方面,电针优于对照组;而在减少VAS评分[MD=﹣0.06,95%CI(﹣0.59,0.47),P=0.82],降低复发率[OR=0.64,95%CI(0.05,7.45),P=0.54]方面,电针与对照组无差异。结论现有有限证据显示,电针干预三叉神经痛总有效率优于对照组,而电针在减轻三叉神经痛患者VAS评分、降低疾病复发率方面与对照组无差异。但受纳入研究样本量所限,该结论尚需更多高质量试验验证。
Objective To systematically assess the efficacy and safety of electroacupuncture for trigeminal neuralgia. Method Randomized controlled trials of a electroacupuncture treatment for trigeminal neuralgia were sought by a computer search of CNKI,Wan Fang Data,VIP,CBM,PubMed,EMbas and The Cochrane Library.The retrieval time limit was from March 1996 to March 2016. Two reviewers sifted the literature and extracted data independently according to the inclusion and exclusion criteria andthen assessed the riskofbias of the included literatureusing the Cochrane risk of bias assessment tool.Ameta-analysis was made using RevMan 5.3.Result Finally, 12 articles were included with atotal of 847 subjects.The results ofmeta-analysis showed that the total efficacy rate was higher in the electroacupuncture group than in the control group [OR=4.04,95%CI（2.67, 6.13）,P〈0.00001].There were no statistically significant differences in the VAS score [MD=﹣0.06,95%CI（﹣0.59, 0.47）,P=0.82] and the recurrence rate [OR=0.64,95%CI（0.05,7.45）,P=0.54] between the electroacupuncture and control groups.Conclusion The currentlimited evidenceshows that the total efficacy rate fortrigeminal neuralgiais higher in the electroacupuncture group than in the control group.There are no statistically significant differences in the VAS score and the recurrence rate of trigeminal neuralgia between the electroacupuncture and control groups of patients.But the conclusions need more high-qualitytrials for validation owing to the limitation of the sample size of the included studies.
作者
周杰
梁宜
陈勤
陈贞羽
方剑乔
ZHOU Jie LIANG Yi CHEN Qin CHEN Zhen-yu FANG Jian-qiao(Zhejiang University of Traditional Chinese Medicine Third Hospital, Hangzhou 310005,China Xiacheng District People＇s Hospital of Hangzhou, Hangzhou 310000,China Zhejiang University of Traditional Chinese Medicine,Hangzhou 310053,China)
出处
《上海针灸杂志》
2017年第4期478-483,共6页
Shanghai Journal of Acupuncture and Moxibustion
基金
浙江省重点科技创新团队(2013TD15)
浙江省中医药科研基金项目(2015ZA116
2016ZA109)
关键词
针刺
电针
三叉神经痛
META分析
Acupuncture
Electroacupuncture
Trigeminal neuralgia
Meta-analysis
