摘要
人肠道病毒D68型属于小RNA病毒科、肠道病毒属、D组病毒,1962年发现于美国加利福尼亚州儿童鼻咽拭子中,后来罕有报道。近年来该病毒在全球多个国家引致暴发,并出现以呼吸及中枢神经系统疾病为主要症状的重症患者,因而引起广泛关注。然而,EV-D68暴发的缘由尚不清楚,当前迫切需要研发特异有效的预防及治疗药物来遏制病毒的危害。本文就EV-D68已有研究进展作一综述,为该病毒后续研究提供依据。
Human enterovirus D68 （EV-D68） is a member of the species Enterovirus D in the genus Enterovirus of the Picornaviridae family. It was first isolated from a pediatric patient in California （USA） in 1962. The virus has rarely been reported since 1962. However, EV-D68 has caused wide public concern in recent years because of outbreaks worldwide. Patients presented with a severe diseases of the respiratory and central nervous systems. Here, we provide a detailed overview of the current understanding of EV- D68-related virology, epidemiology, clinical syndromes, pathogenesis, and laboratory diagnostics.
出处
《病毒学报》
CAS
CSCD
北大核心
2017年第2期279-283,共5页
Chinese Journal of Virology
