摘要
目的:观察自拟方剂天癸一号对利培酮所致闭经的临床疗效。方法:112例患者随机分为观察组和对照组,观察组服用利培酮的同时配合服用自拟方剂天癸一号,对照组服用利培酮同时配合服用安慰剂,共观察6个月,分别采用PANSS量表、TESS量表评价临床疗效和不良反应。结果:两组患者闭经、泌乳发生率比较,差异有统计学意义(P<0.05);治疗后3个月和6个月,两组患者PANSS评分比较,差异有统计学意义(P<0.05);而治疗后TESS评分比较,差异无统计学意义(P>0.05)。结论:自拟方剂天癸一号对预防及治疗服用利培酮所致闭经效果显著,安全有效。可有效提高患者的临床疗效和服药依从性,对精神分裂症复发的预防起到了积极的作用。
Objective：To observe the self-made prescription ＂ semiaquilegia number one＂ for the prevention and treatment of patients with schizophrenia taking risperidone caused amenorrhea.Methods：112 patients were randomly divided into the observation group and the control group.The observation group was treated with risperidone combined with self-made prescription ＂ semiaquilegia number one＂,and the control group was given risperidone and placebo,a total of 6 months.PANSS scale and TESS scale were used to evaluate the clinical efficacy and adverse reactions.Results：Compared amenorrhea and incidence of lactation of the two groups of patients showed that the difference was statistically significant（P 0.05）;3 months after treatment and at the end of the6 months,there was a significant difference in PANSS score between the two groups（P 0.05）.However,there was no significant difference in TESS score after treatment（P 0.05）.Conclusion：Self-made prescription ＂ semiaquilegia number one＂ for the prevention and treatment of patients with amenorrhea caused by risperidone has significant effect,safe and effective,which can effectively improve clinical curative effect and the drug compliance of patients,the positive role to prevent the recurrence of schizophrenia.
出处
《中医学报》
CAS
2017年第4期655-657,共3页
Acta Chinese Medicine
基金
衡水市科技支撑计划项目(201410Z)
关键词
闭经
利培酮
天癸一号
中医药治疗
中西医结合
amenorrhea
risperidone
Semiaquilegia Number One
TCM therapy
combination of traditional Chinese and Western medicine
