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术前外周血中性粒细胞与淋巴细胞计数比鉴别乳腺良恶性肿块的价值 被引量:8

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摘要 目的:分析术前外周血中性粒细胞与淋巴细胞计数比(NLR)在乳腺良恶性肿块鉴别诊断中的价值。方法:回顾性分析天津市肿瘤医院乳腺外科2014年1月1号至2016年9月30号经手术治疗的215例乳腺肿块病人临床资料,根据术后常规病理学检查结果分为良性组和恶性组,对每组病例所对应的NLR进行对比分析,应用ROC曲线分析鉴别乳腺良恶性肿块的最佳临界值。结果:恶性组有较高的中性粒细胞计数及较低的淋巴细胞计数,恶性组NLR明显高于良性组,两组差异有统计学意义(P<0.05)。由ROC曲线分析得出鉴别乳腺肿块良恶性的NLR最佳临界值为1.749,这时灵敏度为86.46,特异度为62.71%。NLR与患者淋巴结转移数、瘤体大小、临床分期和Her-2表达相关。结论:术前外周血NLR值可指导乳腺良恶性肿块的鉴别诊断,高NLR值预示肿块恶性。
作者 林帅 赵颖
出处 《实用医学杂志》 CAS 北大核心 2017年第7期1171-1173,共3页 The Journal of Practical Medicine
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