摘要
目的探讨妊高征经硫酸镁联合拉贝洛尔治疗的临床效果。方法方便选择该院2014年9月—2016年6月收治的妊高症患者102例,采用数字表法分为对照组与联合组,对照组患者应用硫酸镁治疗,联合组在对照组用药基础上联合拉贝洛尔治疗,对比两组患者临床治疗效果及血压、24 h尿蛋白情况。结果联合组总有效率90.20%高与对照组70.59%(P<0.05);观察组治疗后收缩压(129.58±11.69)mmHg、舒张压(84.33±5.26)mmHg、24 h尿蛋白(3.31±1.11)g及对照组收缩压(145.67±12.11)mmHg、舒张压(97.42±6.58)mmHg、24 h尿蛋白(2.14±0.43)g较观察组治疗前收缩压(174.53±10.37)mmHg、舒张压(115.69±9.54)mmHg、24 h尿蛋白(3.31±1.11)g及对照组收缩压(176.31±11.46)mmHg、舒张压(116.41±9.23)mmHg、24 h尿蛋白(3.21±1.24)g相比差异有统计学意义(P<0.05);对照组及研究组患者心率及胎心率[(114.56±14.77)、(146.53±14.32);(112.45±13.61)、(145.74±15.22)次/min]治疗前于治疗后[(108.67±12.32)、(144.61±12.56);(107.58±12.42)、(144.35±11.73)次/min]对比差异无统计学意义(P>0.05)。结论硫酸镁联合拉贝洛尔治疗妊高症的效果较好,值得推广应用。
Objective To discuss the clinical effect of magnesium sulfate and labetalol in treatment of pregnancy-induced hypertension syndrome. Methods 102 cases of patients with syndrome admitted and treated in our hospital from September2014 to June 2016 were selected and divided into two groups, the control group were treated with magnesium sulphuricum,while the combined group were treated with labetalol on the basis of the control group, and the clinical treatment effect,blood hypertension and 24 h urine protein were compared between the two groups. Results The total effective rate in the combined group was higher than that in the control group（90.20%vs 70.59%）（P〈0.05）, and the differences in the systolic pressure, diastolic pressure and 24 h urine protein after treatment between the observation group and the control group had statistical significance[（129.58±11.69）mmHg,（84.33±5.26）mmHg,（3.31±1.11）g vs（145.67±12.11）mmHg,（97.42±6.58）mmHg,（2.14±0.43）g], and the differences in the systolic pressure, diastolic pressure and 24 h urine protein before treatment between the observation group and the control group had statistical significance [（174.53 ±10.37）mmHg,（115.69 ±9.54）mmHg,（3.31±1.11）g vs（176.31±11.46）mmHg,（116.41±9.23）mmHg,（3.21±1.24）g], and the differences in the heart rate and fetal heart rate in the control group and the control group before treatment and after treatment had no statistical significance, [（114.56±14.77）,（146.53±14.32）,（112.45±13.61）,（145.74±15.22）times/min] vs [（108.67±12.32）,（144.61±12.56）;（107.58 ±12.42）,（144.35 ±11.73）times/min]（P〉0.05）. Conclusion The effect of magnesium sulfate and labetalol in treatment of pregnancy-induced hypertension syndrome is better, which is worth promotion and application.
出处
《中外医疗》
2017年第6期110-112,共3页
China & Foreign Medical Treatment
关键词
拉贝洛尔
硫酸镁
妊高征
Labetalol
Magnesium sulfate
Hypertension syndrome
