摘要
目的探讨幽门螺杆菌感染与炎症性肠病的相关性。方法选取炎症性肠病患者52例作为炎症组,其中溃疡性结肠炎患者30例(溃疡性结肠炎组,包括全结肠受累18例与部分结肠受累12例)、Crohn病患者22例(Crohn病组);有消化道症状但肠镜检查正常者60例作为正常组。应用^(14)C尿素呼气试验检测炎症组与正常组幽门螺杆菌感染率。结果炎症组幽门螺杆菌感染率为19.2%(10/52),正常组为46.7%(28/60),炎症组明显低于正常组,差异有统计学意义(P<0.05)。溃疡性结肠炎组幽门螺杆菌感染率为20.0%(6/30),Crohn病组为18.2%(4/22),两组间比较,差异无统计学意义(P>0.05)。溃疡性结肠炎组中,全结肠受累患者幽门螺杆菌感染率为5.6%(1/18),部分结肠受累患者为41.7%(5/12),全结肠受累明显低于部分结肠受累,差异有统计学意义(P<0.05)。结论幽门螺杆菌感染可能预防炎症性肠病的发生与进展。
Objective To explore the relationship of helicobacter pylori infection（ Hp） and inflammatory bowel disease（ IBD）. Methods A total of 52 patients with IBD were involved experimental group including 30 cases of ulcerative colitis（ UC group,including 18 cases of pan-colorectal UC and 12 cases of partial-colorectal UC）,22 cases of Crohn（ Crohn group）;60 cases having digestive symptom while examined normally were in the control group. The infection rates of Hp in the experimental group and control group were analyzed by -（14）C breath test. Results The infection rates of Hp in the experimental group（19. 2%,10/52） was significantly lower than that in the control group（46. 7%,28/60）,and the difference was statistically significant（ P〈0. 05）. There was no statistically significant difference of Hp infection between UC group（20. 0%,6/30） or CD group（18. 2%,4/22）,（ P〈0. 05）. The Hp positive of pancolorectal UC group（5. 6%,1/18） was significantly lower than that of partial-colorectal UC group（41. 7%,5/12）,（ P〈0. 05）. Conclusion Helicobacter pylori infection may prevent the occurrence and progress of the inflammatory bowel disease.
出处
《临床军医杂志》
CAS
2017年第3期232-233,共2页
Clinical Journal of Medical Officers
