摘要
目的复发性流产是育龄妇女常见多发病,中西医结合治疗优势明显,本研究通过探讨补肾疏肝方联合耳穴埋豆法治疗肾虚肝郁型复发性流产临床研究,为其治疗提供思路和方法。方法将100例肾虚肝郁型复发性流产保胎患者按随机数字表法分为对照组(50例)和观察组(50例),对照组肌注黄体酮(20 mg/d),试验组加用口服补肾疏肝方(1剂/d),和耳穴埋豆(2 min/次,3次/d)。观察2组患者的临床疗效、焦虑SAS评分、症状改善情况、血清雌二醇(E2)、孕酮(P)、人绒毛膜促性腺激素(β-HCG)水平及保胎效果,采用SPSS 19.0统计学软件进行数据分析。结果观察组总有效率96.00%,对照组总有效率82.00%,秩和检验差异有统计学意义(P<0.05)。观察组焦虑SAS评分和阴道出血,腹痛、腰酸、小腹下坠感等症候积分显著低于对照组,差异有统计学意义(P<0.05)。观察组血清E2、P及β-HCG显著高于对照组,差异有统计学意义(P<0.05)。随访发现观察组保胎有效率(94.00%)、成功率(90.00%)显著高于对照组(78.00%、74.00%),差异有统计学意义(χ~2=5.316和4.336,P=0.021和0.037)。随SAS积分升高,患者保胎有效率、保胎成功率降低,差异有统计学意义(P<0.05)。结论补肾疏肝方联合耳穴埋豆治疗肾虚肝郁型复发性流产临床疗效确切,可降低焦虑评分,改善临床症状,提高血清激素水平。
Objective The recurrent abortion was a frequently-occurring disease for the women of childbearing age. The combination of traditional Chinese with western medicine had obvious curative effects. By clinically researching tonifying kidney and soothing liver therapy combined with auricular point sticking with beans in abortion patients with kidney deficiency and liver depression, we aim to provide new ideas and methods for treatment. Methods One hundred abortion pa- tients with kidney deficiency and liver depression were divided into the control group（ n = 50） and observation group（ n = 50） according to random number table method. The control group was given intramuscular injection of progesterone, 20 mg/d, and the observation group was given oral prescription of tonifying kidney and soothing liver therapy （ 1 dose per day） combined with auricular point sticking with beans （2 min per time, 3 times per day）. The clinical efficacy, anxiety SAS scores, clinical symptoms were observed in two groups, and the serum levels of estradiol（ E2 ）, progesterone （P） and human ehorionic gonadotropin（β-HCG） were detected. SPSS 19.0 was used for data analysis. Results The total effective rate of observation group was 96.00% ,and that of the control group was 82.00%. The difference had statistical significance in rank sum test（ P 〈 0.05 ）. The scores of anxiety SAS, vaginal bleeding, abdominal pain, lumbar acid and alvine straining feeling in observation group were significantly lower than those in the control group, with statistically significant difference（ P 〈0.05 ）. The levels of E2, P, and β-HCG in observation group were significantly higher than those in the control group, and the difference was statistically significant（ P 〈 0.05 ）. The follow-up found that the efficient and success rate of fetus protection were 94.00% and 90.00% in observation group, which were significantly higher than those in the control group which were 78.00% and 74.00% , with statistical significance （ χ^2= 5. 316,4. 336, P = 0. 021,0. 037 ）. With increasing SAS scores,the total effective rate and success rate of fetus protection were reduced, and the difference was statistically significant （ P 〈 0.05 ）. Conclusion The prescription of tonifying kidney and soothing liver therapy com- bined with auricular point sticking with beans in abortion patients with kidney deficiency and liver depression had clinical curative effect ,which could reduce anxiety score, improve the clinical symptoms, and increase the level of serum hormone.
出处
《中华全科医学》
2017年第5期864-867,共4页
Chinese Journal of General Practice
基金
浙江省中医药科技计划项目(2015ZA199)
浙江省温州市医药卫生科研项目(2016ZA03)
关键词
复发性流产
肾虚肝郁
补肾疏肝方
耳穴埋豆
保胎
Recurrent abortion
Kidney deficiency and liver depression
Tonifying kidney and soothing liver therapy
Auricular point sticking with beans
Fetus protection
