摘要
目的探讨无缝线翼状胬肉切除联合角膜缘干细胞移植手术对复发性翼状胬肉进行治疗的临床效果。方法回顾性分析100例接受手术治疗的复发性翼状胬肉患者的临床资料，随机分为对照组和观察组。对照组采取缝线缝合翼状胬肉切除联合角膜缘干细胞移植术进行治疗，观察组采取无缝线翼状胬肉切除联合角膜缘干细胞及羊膜移植术进行治疗，并对两组治疗结果进行统计对比。所有手术均为一个术者操作，术后随访6—12个月，观察其复发率。结果接受相应治疗后，观察组、对照组治疗总有效率分别为98％、96％，观察组高于对照组；术后复发率分别为2％、4％；两种手术方式术中、术后均无并发症发生，两组比较差异未见统计学意义（P〉0．05）；不同时间点术后疼痛情况比较，观察组明显低于对照组，患者满意度高。结论两种手术方式治疗复发性翼状胬肉均是安全有效的手术方式。
Objective To investigate the clinical effect of the sutureless pterygium excision combined with the corneal limbal stem cell transplantation on relapse pterygium. Methods The clinical data of the 100 patients with relapse pterygium were retrospected analyzed. They had already received the operation and were divided them into the control group and the observation group randomly. The control group received the treatment of the sutures pterygium excision combined with the corneal limbal stem call transplantation, while the observation group received the treatment of the sutureless pterygium excision connected with the corneal limbal stem cell transplantation and amniotic membrane transplantation. After- wards, the statistical comparison was conducted between the treatment outcome of the two groups. All the operations were conducted by the same operator with 6 - 12 months postoperative follow - up in order to observe their relapse rate. Results After receiving the corresponding treatment, the total effective rates of both observation group and control group were 98% and 96% respectively. The effective rate of the observation group was higher than that of the control group. The postoperative recurrent rates of the two groups are 2% and 4% respectively. Complications didnl happen during the two types of operations or after. There are no significant differences between the two groups（ P 〉 0. 05 ）. With the comparison of the pain of occurrence in different time points after the operation, the pain occurrence of the observation group is lower than that of the control group, which achieves higher patients＇satisfaction degree. Conclusions The two types of operations which can cure relapse pterygium are proved to be safe and effective.
出处
《中国实用医刊》
2017年第6期78-80,共3页
Chinese Journal of Practical Medicine
关键词
复发性翼状胬肉
角膜缘干细胞
无缝线
Recurrent pterygium
Corneal limbus stem cells
No stitches
