摘要
目的对药品临床价值的内涵与构成进行分析,并构建药品临床价值评估的指标体系,为药品临床价值的科学评估提供参考依据。方法参考德国、法国药品临床价值评估的指标,初步构建临床价值指标体系,运用专家访谈与德尔菲问卷调查等方法,统计分析确定指标体系构成与指标权重。结果构建了由临床价值和创新价值2个一级指标及15个二级指标组成的药品临床价值分类指标体系。邀请专家根据背景资料对瑞舒伐他汀、阿托伐他汀和辛伐他汀等他汀类药品通用名进行评分,汇总专家评分结果,确定价值排序,并与德国、法国、英国、美国、韩国、日本的市场均价进行对比分析。结论药品临床价值是确定药品合理价格的国际通行标准。本研究依据药品临床价值分类判断药品价格在同类产品中价值排序的方法可行。部分他汀类药品通用名价格排序不能与其临床价值排序相对应,价格没能反映其价值。背景资料的完整性和真实性直接决定临床价值的分级,需要多方参与提供翔实数据和资料。
OBJECTIVE To analyze the connotation and composition of the clinical value of drugs, and to build the index system for the evaluation of drug＇ s clinical value, hence to provide references for its scientific evaluation. METHODS We designed the preliminary constructs index system referencingmedicine clinical evaluation indicatorsof German and French firstly. And then the expert interview and Delphi survey were used to analysis to determine the index system and index weight of medicine clinical evaluation. RESULTS The classified index system of the clinical value was established, which was composed of 2 first- grade indexes including clinical value and innovation value and 15 grade two indexes. Experts were invited to assess the value ranking according to the background information of rosuvastatin, atorvastatin and simvastatin statin drugs by their generic names. The expert＇s scoring results were summarized to determine the sequence. And it were compared with the average market prices in Germany, France, Britain, the United States, South Korea, Japan and analyzed. CONCLUSION The clinical value of drugs is an international standard for determining the reasonable price of drugs. This research method is feasible to determine the drug prices sequencing by the classified clinical value of drugs in the same kind of product. The price sequencing of some generic names of statin drugs did not correspond with its clinical value sequence, and the price can not reflect its value. The integrity and authenticity of the background data directly determine the classification of the clinical value. Various parties are needed to partici-pate in providing detailed data and information.
出处
《中国药学杂志》
CAS
CSCD
北大核心
2017年第8期706-710,共5页
Chinese Pharmaceutical Journal
基金
中国药师协会委托项目"药品临床价值分类研究"项目资助(2015-0-4-092)
