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有创无创序贯机械通气抢救重症呼吸衰竭老年患者的有效性与安全性分析 被引量:14

Safety and efficacy analysis of invasive and non-invasive sequential mechanical ventilation in the treatment of elderly patients with severe respiratory failure
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摘要 目的探讨有创无创序贯机械通气抢救重症呼吸衰竭老年患者的有效性与安全性。方法选取2014年12月~2016年3月在本院接受治疗的64例重症呼吸衰竭老年患者为研究对象,按照随机数字表法分为对照组和观察组,每组32例。对照组患者给予传统机械通气疗法治疗,观察组患者接受有创无创序贯机械通气治疗,比较两组患者的血气分析指标、呼吸、心率,治疗用时以及临床效果。结果观察组患者的PaO_2、SpO_2明显高于对照组,PaCO_2、HR、RR均明显低于对照组(P<0.05)。观察组的总机械通气用时、有创通气用时、住院天数均明显短于对照组,差异有统计学意义(P<0.05)。观察组患者的成功撤机率高于对照组,再次插管率及呼吸机相关肺炎发生率均明显低于对照组(P<0.05)。结论有创无创序贯机械通气用于抢救重症呼吸衰竭老年患者的效果显著,且具有较高的安全性,值得临床广泛推广应用。 Objective To explore the safety and efficacy of invasive and non-invasive sequential mechanical ventilation in the treatment of elderly patients with severe respiratory failure.Methods 64 elderly patients with severe respiratory failure treated in our hospital from December 2014 to March 2016 were selected as study object.Patients were divided into control group and observation group according to random number table method,and each group had 32 cases.The control group was given conventional mechanical ventilation and the observation group was given invasive and non-invasive sequential mechanical ventilation.The blood gas indexes,respiratory (RR) and heart rate (HR),therapeutie time and clinical effect between two groups were compared.Results The PaO2 and SpO2 in observation group were obviously higher than those in control group,while PaCO2,HR and RR were obviously lower than those in control group (P〈0.05).Total mechanical ventilation time,invasive ventilation time and hospital stay in observation group were shorter than those in control group,and the difference was significant (P〈0.05).Rate of successful weaning in observation group was higher than that of control group,and the rate of reintubation and ventilator associated pneumonia were lower than those of control group (P〈0.05).Conclusion Invasive and non-invasive sequential mechanical ventilation in the treatment of elderly patients with severe respiratory failure has a obvious effect,which with higher safety and is worth to be widely used in clinic.
作者 刘建民
出处 《中国当代医药》 2017年第10期27-29,共3页 China Modern Medicine
关键词 有创无创序贯机械通气 抢救 重症呼吸衰竭 老年患者 Invasive and non-invasive sequential mechanical ventilation Rescue Severe respiratory failure Elderly patient
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