摘要
目的探讨二维斑点追踪成像技术评估非ST段抬高型心肌梗死(NSTEMI)患者左心室局部及整体收缩期心肌应变的临床应用。方法选择2011年至2015年解放军总医院的82例NSTEMI患者为NSTEMI组,58例健康人群为对照组。获取两组心尖四腔、两腔及三腔切面二维动态图像,应用斑点追踪技术测定左心室各节段收缩期心肌纵向峰值应变及左室整体心肌纵向应变,应用改良Simpson’s法测量左心室射血分数(LVEF)。结果 NSTEMI组与对照组的LVEF比较,差异无统计学意义[(57±9)%vs.(59±7)%,t=1.651,P=0.101];而NSTEMI组左心室基底段、中间段及心尖段的心肌纵向应变及左室整体心肌纵向应变与对照组相比,均显著降低[(-13±5)%vs.(-18±4)%,(-14±4)%vs.(-19±3)%,(-14±5)%vs.(-18±4)%,(-14±4)%vs.(-18±3)%,t=6.533、7.738、5.025、7.761,P均<0.001]。结论斑点追踪超声成像技术能定量分析NSTEMI患者的心肌纵向应变,可早期准确地评价NSTEMI患者左心室局部及整体心肌收缩功能。
Objective To investigate the clinical application of two-dimensional speckle tracking imaging in assessing the left ventricular regional and global systolic strain in patients with non-ST-segment elevation myocardial infarction（NSTEMI）. Methods This study retrospectively analyzed 82 NSTEMI patients in Chinese PLA General Hospital from 2011 to 2015 as NSTEMI group and 58 healthy people served as the control group. The two-dimensional dynamic images of apical planes in four chamber, two chamber and three chamber were acquired by speckle tracking imaging; the values of left ventricular regional and global strain were obtained. Left ventricular ejection fraction（LVEF） was calculated by the modified Simpson＇s rule. Results LVEF of the NSTEMI group showed no significant difference compared with the control group [（57 ± 9）%vs.（59 ± 7）%, t = 1.651, P = 0.101]. However, compared with the control group, the peak systolic longitudinal strains of each segment at apical, middle and basal levels and left ventricular global strain in the NSTEMI group decreased significantly [（-13 ± 5）% vs.（-18 ± 4）%,（-14 ± 4）% vs.（-19 ± 3）%,（-14 ± 5）% vs.（-18 ± 4）%,（-14 ± 4）% vs.（-18 ± 3）%; t =6.533,7.738, 5.025, 7.761; all P〈0.001]. Conclusion Two dimensional speckle tracking imaging can assess left ventricular longitudinal strains in patients with NSTEMI, and accurately evaluate the left ventricular regional and global systolic function at the early stage.
出处
《中华危重症医学杂志（电子版）》
CAS
CSCD
2017年第1期9-12,共4页
Chinese Journal of Critical Care Medicine:Electronic Edition
基金
国家科技支撑计划课题项目(2012BAI37B04)
关键词
超声心动图
斑点追踪
心肌应变
非ST段抬型高型心肌梗死
Echocardiography
Speckle tracking
Myocardial strain
Non-ST-segment elevation myocardial infarction
